hydroxylation
Sign in to saveIn chemistry, hydroxylation refers to the installation of a hydroxyl group () into an organic compound. Hydroxylations generate alcohols and phenols, which are very common functional groups. Hydroxylation confers some degree of water-solubility. Hydroxylation of a hydrocarbon is an oxidation, thus a step in degradation.
Research
126,121 papers- Enzymatic hydroxylation of aromatic compounds.Cellular and molecular life sciences : CMLS · 2007
- Hydroxylation of Fatty Acids by Lactic Acid Bacteria.Methods in molecular biology (Clifton, N.J.) · 2024
- Hydroxylation of salicylate as an assay for hydroxyl radicals: a cautionary note.Free radical biology & medicine · 1991
- Hydroxylation of salicylate and phenylalanine as assays for hydroxyl radicals: a cautionary note visited for the third time.Free radical research · 1997
- External-Radiation-Induced Local Hydroxylation Enables Remote Release of Functional Molecules in Tumors.Angewandte Chemie (International ed. in English) · 2020
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Wikidata facts
- Subclass of
- chemical reaction
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- facet of
- metabolism
- exact match
- biomodels.net/SBO/SBO_0000233
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Encyclopedic overview
8 sectionsContents
- Atmospheric hydroxylation
- Biological hydroxylation
- Of proteins
- Hydroxylation enzymes
- Synthetic hydroxylations
- Hydroxylation of methane
- Further reading
- References
In chemistry, hydroxylation refers to the installation of a hydroxyl group () into an organic compound. Hydroxylations generate alcohols and phenols, which are very common functional groups. Hydroxylation confers some degree of water-solubility. Hydroxylation of a hydrocarbon is an oxidation, thus a step in degradation.
==Atmospheric hydroxylation== Hydroxylation via reaction with tropospheric hydroxyl radicals and oxygen is one possible pathway for the degradation of aromatic compounds:
Excerpted from Wikipedia’s “hydroxylation” article, available under the CC BY-SA 4.0 licence.