Structure via PubChem · Public domain (PubChem)
oxytetracycline
Sign in to saveAlso known as Hi-Tet, Microtet, Tetraplex, OXTC, Terramycin, Oxytetracycline amphoteric, Oxyterracin, Oxyterracine
Oxytetracycline is a broad-spectrum tetracycline antibiotic, the second of the group to be discovered.
Key facts
- Drug.pregnancy_AU
- D
- Drug.verifiedrevid
- 464196886
- Drug.IUPAC_name
- (4S,4aR,5S,5aR,6S,12aS)-4-(Dimethylamino)-3,5,6,10,11,12a-hexahydroxy-6-methyl-1,12-dioxo-1,4,4a,5,5a,6,12,12a-octahydrotetracene-2-carboxamide
- Drug.image
- Oxytetracycline.svg
- Drug.image_class
- skin-invert-image
- Drug.image2
- Oxytetracycline-from-xtal-Mercury-3D-balls.png
- Drug.image_class2
- bg-transparent
- Drug.tradename
- Terramycin
- Drug.legal_status
- Rx-only
- Drug.routes_of_administration
- By mouth, topical (eye drop)
- Drug.ATC_prefix
- D06
- Drug.ATC_suffix
- AA03
- Drug.ATC_supplemental
- , , , , ,
- Drug.elimination_half life
- 6–8 hours
- Drug.excretion
- Kidney
- Drug.CAS_number
- 79-57-2
- Drug.PubChem
- 54675779
- Drug.DrugBank
- DB00595
via Wikipedia infobox
Chemical data
- Formula
- C22H24N2O9
- Molecular weight
- 460.4 g/mol
- IUPAC name
- (4S,4aR,5S,5aR,6S,12aR)-4-(dimethylamino)-1,5,6,10,11,12a-hexahydroxy-6-methyl-3,12-dioxo-4,4a,5,5a-tetrahydrotetracene-2-carboxamide
- SMILES
- C[C@@]1([C@H]2[C@@H]([C@H]3[C@@H](C(=O)C(=C([C@]3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)N)N(C)C)O)O
- InChIKey
- OWFJMIVZYSDULZ-PXOLEDIWSA-N
- XLogP
- -1.6
- Polar surface area
- 202 Ų
- H-bond donors
- 7
- H-bond acceptors
- 10
- Formal charge
- 0
via PubChem
Research
10,585 papers- Oxytetracycline.Journal of the American Pharmaceutical Association · 1975
- Oxytetracycline.The Practitioner · 1956
- OXYTETRACYCLINE (terramycin).Tubercle · 1955
- [Oxytetracycline--mechanism of action and application in skin diseases].Wiadomosci lekarskie (Warsaw, Poland : 1960) · 2006
- [Oxytetracycline].Therapie · 1958
via PubMed
~9 min read
Encyclopedic overview
6 sectionsContents
- Medical uses
- Side effects
- History
- Biosynthesis
- Veterinary indications
- References
Oxytetracycline is a broad-spectrum tetracycline antibiotic, the second of the group to be discovered.
Oxytetracycline works by interfering with the ability of bacteria to produce essential proteins. Without these proteins, the bacteria cannot grow, multiply and increase in numbers. Oxytetracycline therefore stops the spread of the infection, and the remaining bacteria are killed by the immune system or eventually die.
Excerpted from Wikipedia’s “oxytetracycline” article, available under the CC BY-SA 4.0 licence.