Structure via PubChem · Public domain (PubChem)
idébénone
Sign in to saveAlso known as 2-(10-hydroxydecyl)-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione, 2,3-dimethoxy-5-methyl-6-(10'-hydroxydecyl)-1,4-benzoquinone, 6-(10-hydroxydecyl)-2,3-dimethoxy-5-methyl-1,4-benzoquinone, CV 2619, 2-(10-hydroxydecyl)-5,6-dimethoxy-3-methyl-p-benzoquinone, BRN 2001459, 6-(10-hydroxydecyl)-2,3-dimethoxy-5-methyl-p-benzoquinone
composé chimique
Chemical data
- Formula
- C19H30O5
- Molecular weight
- 338.4 g/mol
- IUPAC name
- 2-(10-hydroxydecyl)-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione
- SMILES
- CC1=C(C(=O)C(=C(C1=O)OC)OC)CCCCCCCCCCO
- InChIKey
- JGPMMRGNQUBGND-UHFFFAOYSA-N
- XLogP
- 4.3
- Polar surface area
- 72.8 Ų
- H-bond donors
- 1
- H-bond acceptors
- 5
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Small molecule
- First approval
- 2015
- Indications
- MELAS, primary progressive multiple sclerosis, attention deficit hyperactivity disorder, non-alcoholic fatty liver disease
via ChEMBL · EBI
Research
850 papers- Idebenone: Clinical Potential Beyond Neurological Diseases.Drug design, development and therapy · 2025
- Idebenone: When an antioxidant is not an antioxidant.Redox biology · 2021
- Therapeutic benefit of idebenone in patients with Leber hereditary optic neuropathy: The LEROS nonrandomized controlled trial.Cell reports. Medicine · 2024
- Idebenone in Friedreich's ataxia.Expert opinion on pharmacotherapy · 2008
- Idebenone vs. rAAV2-ND4 gene therapy in the treatment of Leber's hereditary optic neuropathy: An indirect comparison meta-analysis.Indian journal of ophthalmology · 2025
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Has part
- carbon
- Mass
- 338.209324
- Has use
- medication
Show 6 more facts
- chemical formula
- C₁₉H₃₀O₅
- canonical SMILES
- CC1=C(C(=O)C(=C(C1=O)OC)OC)CCCCCCCCCCO
- World Health Organisation international non-proprietary name
- idebenone
- defined daily dose
- 0.9
- subject has role
- antioxidant
- Commons category
- Idebenone
Sources (6)
via Wikidata · CC0
Article · Français
L'idébénone est une molécule de type quinone, en cours de test comme médicaments dans certaines myopathies.
Abstract from DBpedia / Wikipedia · CC BY-SA