IFT81
Sign in to saveAlso known as CDV-1, CDV-1R, CDV1, CDV1R, DV1, intraflagellar transport 81, SRTD19
Intraflagellar transport protein 81 homolog is a protein that in humans is encoded by the IFT81 gene. Together with IFT74/72 it forms a core complex to build IFT particles which are required for cilium formation. Additionally, it interacts with basal body components as CEP170 which regulates the disassembly of the cilium.
Gene data
IFT81- Name
- intraflagellar transport 81
- Type
- protein-coding
- Aliases
- CDV-1, CDV-1R, CDV1, CDV1R, DV1, SRTD19
The protein encoded by this gene, together with IFT74, forms a tubulin-binding module of intraflagellar transport complex B. This module is involved in transport of tubulin within the cilium, and the encoded protein is required for ciliogenesis. Mutations in this gene are a cause of short-rib polydactyly syndromes. [provided by RefSeq, Dec 2016].
via MyGene.info
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 7664
- exact match
- identifiers.org/ncbigene/28981
- genomic end
- 110218793
- genomic start
- 110562140
- cytogenetic location
- 12q24.11
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Article
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- References
- Further reading
Intraflagellar transport protein 81 homolog is a protein that in humans is encoded by the IFT81 gene. Together with IFT74/72 it forms a core complex to build IFT particles which are required for cilium formation. Additionally, it interacts with basal body components as CEP170 which regulates the disassembly of the cilium.
==References==