IGF2BP2
Sign in to saveAlso known as IMP-2, IMP2, VICKZ2, insulin like growth factor 2 mRNA binding protein 2
Gen der Spezies Homo sapiens
Gene data
IGF2BP2- Name
- insulin like growth factor 2 mRNA binding protein 2
- Type
- protein-coding
- Position
- 185,643,130–185,825,309 (−)
- Aliases
- IMP-2, IMP2, VICKZ2
- Ensembl
- ENSG00000073792
- RefSeq RNA
- NM_001007225.3, NM_001291869.3, NM_001291872.3, NM_001291873.3, NM_001291874.3
- RefSeq protein
- NP_001007226.1, NP_001278798.1, NP_001278801.1, NP_001278802.1, NP_001278803.1
This gene encodes a protein that binds the 5' UTR of insulin-like growth factor 2 (IGF2) mRNA and regulates its translation. It plays an important role in metabolism and variation in this gene is associated with susceptibility to diabetes. Alternative splicing and promoter usage results in multiple transcript variants. Related pseudogenes are found on several chromosomes. [provided by RefSeq, Sep 2016].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
insulin like growth factor 2 mRNA binding protein 2
- Symbol
- IGF2BP2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 3:185,643,130-185,825,309
- Strand
- Reverse (−)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein IGF2BP2 PDB 2cqh.png
Show 8 more facts
- HomoloGene ID
- 4774
- genetic association
- gestational diabetes
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/10644
- genomic end
- 185825042
- genomic start
- 185643130
- chromosome
- human chromosome 3
- cytogenetic location
- 3q27.2
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