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iodocholesterol
Sign in to saveAlso known as 19-iodocholesterol
Iodocholesterol, or 19-iodocholesterol, also as iodocholesterol (131I) (INN) and NP-59, is a derivative of cholesterol with an iodine atom in the C19 position and a radiopharmaceutical. When the iodine atom is a radioactive isotope (iodine-125 or iodine-131), it is used as an adrenal cortex radiotracer in the diagnosis of patients suspected of having Cushing's syndrome, hyperaldosteronism, pheochromocytoma, and adrenal remnants following total adrenalectomy.
Research
256 papers- Radiation dosimetry of 131I-19-iodocholesterol.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 1973
- Iodocholesterol adrenal tissue uptake and imaging adrenal neoplasms.The Journal of clinical endocrinology and metabolism · 1981
- Adrenocortical scintigraphy.Rays · 1992
- Scintigraphy with 131I-19-iodocholesterol in adrenal disease.Acta medica Scandinavica · 1975
- Functional imaging of adrenal cortex.Revista espanola de medicina nuclear e imagen molecular · 2020
via PubMed
Wikidata facts
- Mass
- 512.252
Show 3 more facts
- canonical SMILES
- CC(C)CCCC(C)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)O)CI)C
- chemical formula
- C₂₇H₄₅IO
- isomeric SMILES
- C[C@H](CCCC(C)C)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC=C4[C@@]3(CC[C@@H](C4)O)CI)C
Sources (2)
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Article
1 sectionsContents
- References
Iodocholesterol, or 19-iodocholesterol, also as iodocholesterol (131I) (INN) and NP-59, is a derivative of cholesterol with an iodine atom in the C19 position and a radiopharmaceutical. When the iodine atom is a radioactive isotope (iodine-125 or iodine-131), it is used as an adrenal cortex radiotracer in the diagnosis of patients suspected of having Cushing's syndrome, hyperaldosteronism, pheochromocytoma, and adrenal remnants following total adrenalectomy.
== References ==