Structure via PubChem · Public domain (PubChem)
isocytosine
Sign in to saveAlso known as 2-amino-4-hydroxypyrimidine, 2-amino-4-pyrimidone, 2-amino-4-pyrimdinol, 2-amino-4-oxypyrimidine
Isocytosine or 2-aminouracil is a pyrimidine base that is an isomer of cytosine. The nucleoside form is called isocytidine (iC).
Chemical data
- Formula
- C4H5N3O
- Molecular weight
- 111.1 g/mol
- IUPAC name
- 2-amino-1H-pyrimidin-6-one
- SMILES
- C1=CN=C(NC1=O)N
- InChIKey
- XQCZBXHVTFVIFE-UHFFFAOYSA-N
- XLogP
- -1
- Polar surface area
- 67.5 Ų
- H-bond donors
- 2
- H-bond acceptors
- 2
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Molecule type
- Small molecule
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 111.043
Show 3 more facts
- chemical formula
- C₄H₅N₃O
- canonical SMILES
- C1=CN=C(NC1=O)N
- Commons category
- Isocytosine
Sources (1)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- Synthesis
- Uses
- References
Isocytosine or 2-aminouracil is a pyrimidine base that is an isomer of cytosine. The nucleoside form is called isocytidine (iC).
It is used in combination with isoguanine in studies of unnatural nucleic acid analogues of the normal base pairs in DNA. In particular, it is used as a nucleobase of hachimoji RNA with the abbreviation rS.
Excerpted from Wikipedia’s “isocytosine” article, available under the CC BY-SA 4.0 licence.