isoguanine
Isoguanine or 2-hydroxyadenine is a purine base that is an isomer of guanine. The nucleoside form is called isoguanosine (iG).
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Isoguanine or 2-hydroxyadenine is a purine base that is an isomer of guanine. The nucleoside form is called isoguanosine (iG).
It is a product of oxidative damage to DNA in cultured E. coli and human cells. However, newer evidence shows that it mainly occurs in RNA and as the ribonucleoside instead of in DNA or as deoxyribonucleoside in living mammals, calling into question its link with DNA in vivo.