ITIH3
Sign in to saveAlso known as H3P, ITI-HC3, SHAP, inter-alpha-trypsin inhibitor heavy chain 3
Inter-alpha-trypsin inhibitor heavy chain H3 is a protein that in humans is encoded by the ITIH3 gene.
Gene data
ITIH3- Name
- inter-alpha-trypsin inhibitor heavy chain 3
- Type
- protein-coding
- Position
- 52,794,450–52,809,881 (+)
- Aliases
- H3P, ITI-HC3, SHAP
- Ensembl
- ENSG00000162267
- RefSeq RNA
- NM_001392019.1, NM_001392020.1, NM_001392021.1, NM_001392022.1, NM_001392023.1
- RefSeq protein
- NP_001378948.1, NP_001378949.1, NP_001378950.1, NP_001378951.1, NP_001378952.1
This gene encodes the heavy chain subunit of the pre-alpha-trypsin inhibitor complex. This complex may stabilize the extracellular matrix through its ability to bind hyaluronic acid. Polymorphisms of this gene may be associated with increased risk for schizophrenia and major depressive disorder. This gene is present in an inter-alpha-trypsin inhibitor family gene cluster on chromosome 3. [provided by RefSeq, Jul 2015].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
inter-alpha-trypsin inhibitor heavy chain 3
- Symbol
- ITIH3
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 3:52,794,450-52,809,881
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 1669
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/3699
- genomic end
- 52843025
- genomic start
- 52828784
- chromosome
- human chromosome 3
- cytogenetic location
- 3p21.1
- expressed in
- sperm
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- See also
- References
- Further reading
Inter-alpha-trypsin inhibitor heavy chain H3 is a protein that in humans is encoded by the ITIH3 gene.
== See also == Inter-alpha-trypsin inhibitor ITIH1 ITIH2 ITIH4
Excerpted from Wikipedia’s “ITIH3” article, available under the CC BY-SA 4.0 licence.