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JWH-147
Sign in to saveJWH-147 is an analgesic drug used in scientific research, which acts as a cannabinoid agonist at both the CB1 and CB2 receptors. It is somewhat selective for the CB2 subtype, with a Ki of 11.0 nM at CB1 vs 7.1 nM at CB2. It was discovered and named after the renowned professor of organic chemistry John W. Huffman.
Chemical data
- Formula
- C27H27NO
- Molecular weight
- 381.5 g/mol
- IUPAC name
- (1-hexyl-5-phenylpyrrol-3-yl)-naphthalen-1-ylmethanone
- SMILES
- CCCCCCN1C=C(C=C1C2=CC=CC=C2)C(=O)C3=CC=CC4=CC=CC=C43
- InChIKey
- FRMYAMAGHYHNKF-UHFFFAOYSA-N
- XLogP
- 7.2
- Polar surface area
- 22 Ų
- H-bond donors
- 0
- H-bond acceptors
- 1
- Formal charge
- 0
via PubChem
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 381.209264484
Show 3 more facts
- canonical SMILES
- CCCCCCN1C=C(C=C1C2=CC=CC=C2)C(=O)C3=CC=CC4=CC=CC=C43
- Commons category
- JWH-147
- chemical formula
- C₂₇H₂₇NO
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- Legal status
- See also
- References
JWH-147 is an analgesic drug used in scientific research, which acts as a cannabinoid agonist at both the CB1 and CB2 receptors. It is somewhat selective for the CB2 subtype, with a Ki of 11.0 nM at CB1 vs 7.1 nM at CB2. It was discovered and named after the renowned professor of organic chemistry John W. Huffman.
==Legal status== In the United States, CB1 receptor agonists of the 3-(1-naphthoyl)pyrrole class such as JWH-147 are Schedule I Controlled Substances.
Excerpted from Wikipedia’s “JWH-147” article, available under the CC BY-SA 4.0 licence.