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JWH-398
Sign in to saveJWH-398 is an analgesic chemical from the naphthoylindole family, which acts as a cannabinoid agonist at both the CB1 and CB2 receptors. It has mild selectivity for CB1 with a Ki of 2.3 nM and 2.8 nM at CB2. This synthetic chemical compound was identified by the EMCDDA as an ingredient in three separate "herbal incense" products purchased from online shops between February and June 2009. It was discovered by, and named after, John W. Huffman.
Chemical data
- Formula
- C24H22ClNO
- Molecular weight
- 375.9 g/mol
- IUPAC name
- (4-chloronaphthalen-1-yl)-(1-pentylindol-3-yl)methanone
via PubChem
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 375.139
Show 3 more facts
- chemical formula
- C₂₄H₂₂ClNO
- canonical SMILES
- CCCCCN1C=C(C2=CC=CC=C21)C(=O)C3=CC=C(C4=CC=CC=C43)Cl
- Commons category
- JWH-398
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- See also
- References
JWH-398 is an analgesic chemical from the naphthoylindole family, which acts as a cannabinoid agonist at both the CB1 and CB2 receptors. It has mild selectivity for CB1 with a Ki of 2.3 nM and 2.8 nM at CB2. This synthetic chemical compound was identified by the EMCDDA as an ingredient in three separate "herbal incense" products purchased from online shops between February and June 2009. It was discovered by, and named after, John W. Huffman.
In the United States, JWH-398 is a Schedule I controlled substance.
Excerpted from Wikipedia’s “JWH-398” article, available under the CC BY-SA 4.0 licence.