Lanosterol synthase
Sign in to saveAlso known as 2,3-epoxysqualene-lanosterol cyclase, epididymis secretory sperm binding protein, OSC, hOSC, LSS, 2,3-epoxysqualene--lanosterol cyclase, oxidosqualene--lanosterol cyclase
mammalian protein found in Homo sapiens
Protein · UniProt
Lanosterol synthase
- Gene
- LSS
- Organism
- Homo sapiens (Human)
- Length
- 732 aa
- Molecular mass
- 83,309 Da
- Evidence
- 1: Evidence at protein level
Key enzyme in the cholesterol biosynthesis pathway. Catalyzes the cyclization of (S)-2,3 oxidosqualene to lanosterol, a reaction that forms the sterol nucleus (PubMed:14766201, PubMed:26200341, PubMed:7639730). Through the production of lanosterol may regulate lens protein aggregation and increase transparency (PubMed:26200341)
3D-structureAcetylationAlternative splicingCataractDirect protein sequencingDisease variantEndoplasmic reticulumHypotrichosis
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Swiss-Prot (reviewed) · via UniProt
Wikidata facts
- Instance of
- protein
Show 3 more facts
- cell component
- lipid droplet
- found in taxon
- Homo sapiens
- exact match
- purl.uniprot.org/uniprot/P48449
Sources (3)
via Wikidata · CC0