Phosphoglycerate mutase
Sign in to saveAlso known as PGA mutase, monophosphoglyceromutase, monophosphoglycerate mutase, PGAM, phosphoglycerate phosphomutase, D-phosphoglycerate 2,3-phosphomutase, PGM, phosphoglyceromutase
class of enzymes
Research
1,270 papers- Thermal proteome profiling reveals fructose-1,6-bisphosphate as a phosphate donor to activate phosphoglycerate mutase 1.Nature communications · 2024
- Phosphoglycerate mutase 5 initiates inflammation in acute kidney injury by triggering mitochondrial DNA release by dephosphorylating the pro-apoptotic protein Bax.Kidney international · 2023
- Phosphoglycerate mutase 1-mediated dephosphorylation and degradation of Dusp1 disrupt mitochondrial quality control and exacerbate endotoxemia-induced myocardial dysfunction.Theranostics · 2024
- Phosphoglycerate mutase 1 in cancer: A promising target for diagnosis and therapy.IUBMB life · 2019
- A Novel Allosteric Inhibitor of Phosphoglycerate Mutase 1 Suppresses Growth and Metastasis of Non-Small-Cell Lung Cancer.Cell metabolism · 2019
via PubMed
Wikidata facts
- Image
- Homodimer B-type PGM.png
Show 2 more facts
- Commons category
- Phosphoglycerate mutase
- EC enzyme number
- 5.4.2.11
via Wikidata · CC0
Connections
(RS)-3-phosphoglyceric acid
Entity
2-phosphoglyceric acid
Entity
DL-glyceric acid 1,3-biphosphate
Entity
2,3-diphosphoglyceric acid
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protein superfamily
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enzyme
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metabolism
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ion
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glucose
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digital object identifier
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glycerol
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phosphates
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glycolytic process
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L-alanine
Entity
DL-lactic acid
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Q180686
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tricarboxylic acid cycle
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L-aspartic acid
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bibcode
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L-histidine
Entity