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Ledol

Structure via PubChem · Public domain (PubChem)

EntityQ19291552· pop 5· linked from 165 articles

Ledol is a poisonous sesquiterpene that can cause cramps, paralysis, and delirium. Caucasian peasants used Rhododendron plants for these effects in shamanistic rituals. Ledol resides in the essential oils of certain plants and when crushed, these oils are released. One of the plants with the highest concentration of these essential oils is Rhododendron tomentosum.

Chemical data

Formula
C15H26O
Molecular weight
222.37 g/mol
IUPAC name
(1aR,4R,4aS,7R,7aS,7bS)-1,1,4,7-tetramethyl-2,3,4a,5,6,7,7a,7b-octahydro-1aH-cyclopropa[e]azulen-4-ol
SMILES
C[C@@H]1CC[C@H]2[C@@H]1[C@H]3[C@H](C3(C)C)CC[C@@]2(C)O
InChIKey
AYXPYQRXGNDJFU-AOWZIMASSA-N
XLogP
3.7
Polar surface area
20.2 Ų
H-bond donors
1
H-bond acceptors
1
Formal charge
0

via PubChem

Wikidata facts

Mass
222.198365
Show 4 more facts
found in taxon
Eucalyptus dealbata
chemical formula
C₁₅H₂₆O
isomeric SMILES
C[C@@H]1CC[C@H]2[C@@H]1[C@H]3[C@H](C3(C)C)CC[C@@]2(C)O
canonical SMILES
CC1CCC2C1C3C(C3(C)C)CCC2(C)O
Sources (1)

via Wikidata · CC0

~4 min read

Encyclopedic overview

5 sections
Contents
  • Historical and traditional uses
  • Mechanism of action
  • Metabolism
  • Sources
  • References

Ledol is a poisonous sesquiterpene that can cause cramps, paralysis, and delirium. Caucasian peasants used Rhododendron plants for these effects in shamanistic rituals. Ledol resides in the essential oils of certain plants and when crushed, these oils are released. One of the plants with the highest concentration of these essential oils is Rhododendron tomentosum.

The word "ledol" comes from the Greek word "ledos" meaning "robe". This likely comes from the "wooly" appearance of the plant, which has hair-like stalks stemming from the flower.

Excerpted from Wikipedia’s “Ledol” article, available under the CC BY-SA 4.0 licence.

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