Leigh disease
Sign in to saveAlso known as Infantile necrotizing encephalomyelopathy, LEIGH SYNDROME, Leigh's disease (disorder), juvenile subacute necrotizing encephalomyelopathy, subacute necrotizing encephalomyelopathy
mitochondrial metabolism disease characterized by progressive loss of mental and movement abilities. Symptoms usually begin between ages of three months and two years and include loss of appetite, vomiting, irritability and seizure activity
In the Vinony graph
Within Vinony's link graph, Leigh disease is referenced by 331 other articles, and connects out to bilirubin, brain stem and demyelinating disease.
Vinony files it under Diseases named after discoverers, Mitochondrial diseases and Neurological disorders.
Its subject is documented across 16 Wikipedia language editions.
Research
3,733 papers- Leigh syndrome.Handbook of clinical neurology · 2023
- Leigh syndrome: One disorder, more than 75 monogenic causes.Annals of neurology · 2016
- A guide to diagnosis and treatment of Leigh syndrome.Journal of neurology, neurosurgery, and psychiatry · 2014
- Exclusion of sulfide:quinone oxidoreductase from mitochondria causes Leigh-like disease in mice by impairing sulfide metabolism.The Journal of clinical investigation · 2024
- Leigh's disease.The Medical journal of Australia · 1986
via PubMed
Wikidata facts
- Subclass of
- disease
Show 7 more facts
- health specialty
- neurology
- NCI Thesaurus ID
- C84814
- genetic association
- SURF1
- exact match
- www.orpha.net/ORDO/Orphanet_506
- on focus list of Wikimedia project
- WikiProject Medicine
- symptoms and signs
- vomiting
- Commons category
- Leigh syndrome
via Wikidata · CC0