白血病

Key facts

Medical condition.name

Leukemia

Medical condition.synonyms

Leukaemia

Medical condition.image

ALL-AML.jpg

Medical condition.caption

A Wright's stained bone marrow aspirate smears from individuals with B-cell acute lymphoblastic leukemia (left) and acute myeloid leukemia (right). Myeloid leukemia cells are usually larger, contain prominent nucleoli, and specific, but not mandatory, cytoplasmic inclusions – Auer rods (purple needles).

Medical condition.field

Hematology and oncology

Medical condition.symptoms

Bleeding, bruising, fatigue, fever, increased risk of infections

Medical condition.onset

All ages, most common in 60s and 70s. It is the most common malignant cancer in children, but the cure rates are also higher for them.

Medical condition.causes

Inherited and environmental factors

Medical condition.risks

Smoking, family history, ionizing radiation, some chemicals such as trichloroethylene, prior chemotherapy, Down syndrome.

Medical condition.diagnosis

Blood tests, bone marrow biopsy

Medical condition.treatment

Chemotherapy, radiation therapy, targeted therapy, bone marrow transplant, supportive care

Medical condition.prognosis

Five-year survival rate 68% (U.S.)

Medical condition.frequency

2.3 million (2015)

Medical condition.deaths

353,500 (2015)

via Wikipedia infobox

• Leukemia's Next Top Model? Syngeneic Models to Advance Adoptive Cellular Therapy.ReviewFrontiers in immunology · 2022Zoine JT, Moore SE, Velasquez MPDOI: 10.3389/fimmu.2022.867103
• Multiparameter flow cytometry in the diagnosis and management of acute leukemia.ReviewArchives of pathology & laboratory medicine · 2011Peters JM, Ansari MQDOI: 10.5858/2010-0387-RAR.1
• The molecular and clinical significance of the Tie/angiopoietin system in leukemia.ReviewPathology, research and practice · 2023Vedadi S, Azimzadeh M, Touluei AE et al.DOI: 10.1016/j.prp.2022.154285
• Chronic lymphocytic leukaemia.ReviewCritical reviews in oncology/hematology · 2016Scarfò L, Ferreri AJ, Ghia PDOI: 10.1016/j.critrevonc.2016.06.003
• Type I interferons: leukemia's old foe in the limelight again.Haematologica · 2024Kumar A, Swaminathan SDOI: 10.3324/haematol.2024.285079
• Adipocytes in hematopoiesis and acute leukemia: friends, enemies, or innocent bystanders?ReviewLeukemia · 2020Zinngrebe J, Debatin KM, Fischer-Posovszky PDOI: 10.1038/s41375-020-0886-x
• Proposals for the classification of the acute leukaemias. French-American-British (FAB) co-operative group.British journal of haematology · 1976Bennett JM, Catovsky D, Daniel MT et al.DOI: 10.1111/j.1365-2141.1976.tb03563.x
• Advances in germline predisposition to acute leukaemias and myeloid neoplasms.ReviewNature reviews. Cancer · 2021Klco JM, Mullighan CGDOI: 10.1038/s41568-020-00315-z

via PubMed

Wikidata facts

Instance of

symptom or sign

Subclass of

disease

Official name

白血病

Image

Symptoms of leukemia-hy.svg

via Wikidata · CC0