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GeneQ18028540· pop 6· linked from 11 articles

Also known as Gal-8, PCTA-1, PCTA1, Po66-CBP, galectin 8

Galectin-8 is a protein of the galectin family that in humans is encoded by the LGALS8 gene.

Gene data

LGALS8
Name
galectin 8
Type
protein-coding
Position
236,518,000–236,552,981 (+)
Aliases
Gal-8, PCTA-1, PCTA1, Po66-CBP
RefSeq RNA
NM_006499.5, NM_201543.4, NM_201544.4, NM_201545.2, XM_011544188.4
RefSeq protein
NP_006490.3, NP_963837.1, NP_963838.1, NP_963839.1, XP_011542490.1

This gene encodes a member of the galectin family. Galectins are beta-galactoside-binding animal lectins with conserved carbohydrate recognition domains. The galectins have been implicated in many essential functions including development, differentiation, cell-cell adhesion, cell-matrix interaction, growth regulation, apoptosis, and RNA splicing. This gene is widely expressed in tumoral tissues and seems to be involved in integrin-like cell interactions. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].

via MyGene.info

Gene · Ensembl

galectin 8

Symbol
LGALS8
Biotype
Protein coding
Organism
Homo sapiens
Location
1:236,518,000-236,552,981
Strand
Forward (+)
Assembly
GRCh38
View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of
gene
Image
Protein LGALS8 PDB 2YRO.png
Show 8 more facts
HomoloGene ID
31386
found in taxon
Homo sapiens
genomic end
236716281
genomic start
236681300
expressed in
spleen
cytogenetic location
1q43
Sources (3)

via Wikidata · CC0

~3 min read

Encyclopedic overview

8 sections
Contents
  • Function
  • Galectin-8 levels
  • Role in cancer
  • Role in cellular defence
  • Engineered galectin-8 assays
  • Interactions
  • References
  • Further reading

Galectin-8 is a protein of the galectin family that in humans is encoded by the LGALS8 gene.

== Function ==

Excerpted from Wikipedia’s “LGALS8” article, available under the CC BY-SA 4.0 licence.

Available in 6 languages

via Wikidata sitelinks · CC0