lucimycin

Lucimycin (INN, also known as lucensomycin and etruscomycin) is a macrolide antibiotic synthesized by the bacterium Streptomyces lucensis. It belongs to the group of polyene antimycotics and was first isolated in the 1960s. It has seen only limited clinical use.

Research

49 papers

[Molecular Characterization of Lucimycin Gene of Lucilia sericata].Mikrobiyoloji bulteni · 2020
Lucimycin, an antifungal peptide from the therapeutic maggot of the common green bottle fly Lucilia sericata.Biological chemistry · 2014
[Lucifensin, Chymotrypsin Proteins and Molecular Characterization of Lucilia sericata].Mikrobiyoloji bulteni · 2021
Selection and Evaluation of Tissue Specific Reference Genes in Lucilia sericata during an Immune Challenge.PloS one · 2015
Antimicrobial peptides expressed in medicinal maggots of the blow fly Lucilia sericata show combinatorial activity against bacteria.Antimicrobial agents and chemotherapy · 2015

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Wikidata facts

Mass: 707.3516907559998

Show 3 more facts

chemical formula: C₃₆H₅₃NO₁₃
isomeric SMILES: CCCCC1C/C=C/C=C/C=C/C=C/C(CC2C(C(CC(O2)(CC(CC3C(O3)/C=C/C(=O)O1)O)O)O)C(=O)O)O[C@H]4[C@H]([C@H]([C@@H]([C@H](O4)C)O)N)O
canonical SMILES: CCCCC1CC=CC=CC=CC=CC(OC2OC(C)C(O)C(N)C2O)CC2OC(O)(CC(O)CC3OC3C=CC(=O)O1)CC(O)C2C(=O)O

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References
Further reading

Lucimycin is also produced by the Streptomyces cyanogenus S136, where the full biosynthetic gene cluster for the production of this compound was described.