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EntityQ407727· pop 34· linked from 6,234 articles

Also known as lyases

In biochemistry, a lyase is an enzyme that catalyzes the breaking (an elimination reaction) of various chemical bonds by means other than hydrolysis (a substitution reaction) and oxidation, often forming a new double bond or a new ring structure. The reverse reaction is also possible (called a Michael reaction). For example, an enzyme that catalyzed this reaction would be a lyase:

Research

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Encyclopedic overview

5 sections
Contents
  • Nomenclature
  • Classification
  • Membrane-associated lyases
  • See also
  • References

In biochemistry, a lyase is an enzyme that catalyzes the breaking (an elimination reaction) of various chemical bonds by means other than hydrolysis (a substitution reaction) and oxidation, often forming a new double bond or a new ring structure. The reverse reaction is also possible (called a Michael reaction). For example, an enzyme that catalyzed this reaction would be a lyase: ATP → cAMP + PPi

Lyases differ from other enzymes in that they require only one substrate for the reaction in one direction, but two substrates for the reverse reaction.

Excerpted from Wikipedia’s “lyase” article, available under the CC BY-SA 4.0 licence.