malacidin
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Malacidins are a class of chemicals made by bacteria found in soil that can kill Gram-positive bacteria. Their activity appears to be dependent on calcium. The discovery of malacidins was published in 2018.
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Encyclopedic overview
6 sectionsContents
- Chemical structure
- Mechanism of action
- History
- Research directions
- See also
- References
Malacidins are a class of chemicals made by bacteria found in soil that can kill Gram-positive bacteria. Their activity appears to be dependent on calcium. The discovery of malacidins was published in 2018.
The malacidin family were discovered using a new method of soil microbiome screening that does not require cell culturing. This allowed researchers to identify genetic components necessary to produce the chemical. Malacidin A was shown to kill Staphylococcus aureus and other Gram-positive bacteria.
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