File:Malaria_Parasite_Connecting_to_Human_Red_Blood_Cell_(34034143483).jpg · Wikimedia Commons · See Wikimedia Commons

EntityQ12156· pop 194· linked from 6,276 articles

マラリア

Also known as Plasmodium infection, induced malaria, ague, marsh fever

熱帯から亜熱帯に広く分布する原虫感染症

OverviewAI-generated

Malaria is an endemic disease classified as a parasitic protozoa infectious disease and vector-borne disease. It is caused by Plasmodium falciparum, Plasmodium vivax, Plasmodium malariae, and Plasmodium ovale, with Anopheles serving as its natural reservoir. Poverty acts as a contributing factor to the condition. The disease has a minimal incubation period in humans of 7.

Clinical manifestations include intermittent fever, hepatomegaly, anemia, and splenomegaly. Diagnosis involves medical examinations such as blood film analysis, optical microscope usage, and polymerase chain reaction. Health specialties managing the disease include infectious diseases, tropical medicine, and parasitology. Treatments utilize drugs such as chloroquine, (RS)-primaquine, hydroxychloroquine, and mefloquine. Genetic associations involve ABO and ATP2B4.

The condition has been described by sources including the Armenian Soviet Encyclopedia, Brockhaus and Efron Encyclopedic Dictionary, and Encyclopædia Britannica 11th edition. Ronald Ross and Charles Louis Alphonse Laveran are credited as discoverers. Reported statistics indicate 500,000,000 cases and 627,000 deaths, with a disease burden of 216,000,000.

Synthesized by Vinony from 25 facts across 3 sources: Wikidata, PubMed, Vinony graph. Generated from structured data (not the Wikipedia text) and checked against those facts — may still contain errors.

Key facts

Medical condition.name: Malaria
Medical condition.synonym: Ague, paludism, marsh fever
Medical condition.image: Malaria Parasite Connecting to Human Red Blood Cell (34034143483).jpg
Medical condition.caption: Malaria parasite connecting to a red blood cell
Medical condition.field: Infectious disease
Medical condition.symptoms: Mild malaria: fever, chills, vomiting, headache, diarrhea. Severe malaria: anemia, jaundice, coma
Medical condition.complications: seizures, coma, organ failure, anemia, cerebral malaria
Medical condition.onset: usually 10–15 days post exposure
Medical condition.duration: lifelong if not treated
Medical condition.causes: Plasmodium transmitted by Anopheles mosquitoes
Medical condition.risks: Exposure to mosquitoes in Endemic areas
Medical condition.diagnosis: Examination of the blood, antigen detection tests
Medical condition.prevention: Mosquito nets, insect repellent, mosquito control, prophylactic medication
Medical condition.medication: Antimalarial medication
Medical condition.frequency: 263 million (2023)
Medical condition.deaths: 597,000 (2023)

via Wikipedia infobox

Research

124,011 papers

An Overview of Malaria Transmission Mechanisms, Control, and Modeling.ReviewMedical sciences (Basel, Switzerland) · 2022Savi MKDOI: 10.3390/medsci11010003
Overview of Plasmodium spp. and Animal Models in Malaria Research.ReviewComparative medicine · 2024Gozalo AS, Robinson CK, Holdridge J et al.DOI: 10.30802/AALAS-CM-24-000019
Malaria's modelling problem.Nature · 2023Nordling LDOI: 10.1038/d41586-023-02054-1
Non-falciparum malaria infections in Uganda, does it matter? A review of the published literature.ReviewMalaria journal · 2024Ranjbar M, Tegegn Woldemariam YDOI: 10.1186/s12936-024-05023-9
Extracellular Vesicles in Malaria: Shedding Light on Pathogenic Depths.ReviewACS infectious diseases · 2024Dey S, Mohapatra S, Khokhar M et al.DOI: 10.1021/acsinfecdis.3c00649
The Effect of Malaria on Responses to Unrelated Vaccines in Animals and Humans: A Systematic Review and Meta-Analysis.Parasite immunology · 2024Zirimenya L, Natukunda A, Nassuuna J et al.DOI: 10.1111/pim.13067
Malaria in pregnancy and its potential impact on neurodevelopment in children: a systematic review.Pediatric research · 2025Nema S, Singhal R, Bharti PK et al.DOI: 10.1038/s41390-025-03967-5
Animal Models of Malaria-Associated Acute Kidney Injury.ReviewSeminars in nephrology · 2025Mamudu CO, Polidoro R, Gallego-Delgado JDOI: 10.1016/j.semnephrol.2025.151616

via PubMed

Wikidata facts

Subclass of: disease
Named after: wetland
Image: Histopathology of malaria exoerythrocytic forms in liver 07G0024 lores.jpg
Number of deaths: 627000

Show 26 more facts

has natural reservoir: Anopheles
has cause: Plasmodium knowlesi
has contributing factor: poverty
Commons category: Malaria
discoverer or inventor: Charles Louis Alphonse Laveran
topic's main category: Category:Malaria
medical examination: polymerase chain reaction
NCI Thesaurus ID: C34797
health specialty: parasitology
number of cases: 4114
ICPC 2 ID: A73
drug or therapy used for treatment: atovaquone
disease burden: 216000000
exact match: purl.obolibrary.org/obo/DOID_12365
hashtag: Malaria
symptoms and signs: fever
minimal incubation period in humans: 7
maximal incubation period in humans: 30
disease transmission process: blood transfusion
on focus list of Wikimedia project: WikiProject Medicine
ICD-9-CM: 084.6
WordLift URL: data.medicalrecords.com/medicalrecords/healthwise/malaria
possible treatment: symptomatic treatment
P8168: Álvaro Julio Beyra Luarca
different from: miliaria
maintained by WikiProject: WikiProject South Africa

Sources (15)

via Wikidata · CC0

Article · 日本語

マラリア（麻剌利亜、麻拉利亜、ドイツ語: Malaria、英語: malaria、語源は「悪い空気」を意味する古いイタリア語: mala aria）は、熱帯から亜熱帯に広く分布するマラリア原虫による感染症である。雌のハマダラカが媒介するマラリア原虫が病原体であり、原虫の違いにより5種類に大別される（熱帯熱マラリア、三日熱マラリア、四日熱マラリア、卵形マラリア、サルマラリア）。蚊に刺されてマラリア原虫が体内に入ると、潜伏期間（1週間～4週間程度）を経て、発熱や悪寒（寒気）、頭痛、関節や筋肉の痛み、関節痛、筋肉痛、嘔吐、下痢といった症状が現れ、脳や内臓に合併症を引き起こすこともある。防蚊対策のほか、予防薬や治療薬もあるが、熱帯熱マラリアでは発症から24時間以内に適切な治療を施さないと重症化して、死亡することもある。悪性の場合はによる意識障害や腎不全なども起きる。全世界ではマラリアに年間2.16億人が感染し、うち44.5万人が死亡している（2016年）。日本でも輸入感染症として年間60人程度の発症届け出がある（新型コロナウイルス感染症の世界的流行による国際的往来制限前）。近代以前の日本でもしばしば発生しており、古典などで出てくる瘧（おこり）とは、大抵このマラリアを指していた。痎瘧（かいぎゃく、がいぎゃく）はマラリアの意。感染者や死者が多いことから、医学や公衆衛生でも重大な関心が払われており、世界保健機関（WHO）は4月25日を「世界マラリア・デー」に定めている。結核、ヒト免疫不全ウイルス（HIV）とともに「世界三大感染症」と呼ばれる。

Abstract from DBpedia / Wikipedia · CC BY-SA