MFN1
Sign in to saveAlso known as hfzo1, hfzo2, mitofusin 1
Mitofusin-1 is a protein that in humans is encoded by the MFN1 gene.
Gene data
MFN1- Name
- mitofusin 1
- Type
- protein-coding
- Position
- 179,346,952–179,396,566 (+)
- Aliases
- hfzo1, hfzo2
- Ensembl
- ENSG00000171109
- RefSeq RNA
- NM_017927.2, NM_033540.3, XM_005247596.5, XM_011512963.4, XM_054347195.1
- RefSeq protein
- NP_284941.2, XP_005247653.2, XP_011511265.1, XP_054203170.1, XP_054203171.1
The protein encoded by this gene is a mediator of mitochondrial fusion. This protein and mitofusin 2 are homologs of the Drosophila protein fuzzy onion (Fzo). They are mitochondrial membrane proteins that interact with each other to facilitate mitochondrial targeting. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
mitofusin 1
- Symbol
- MFN1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 3:179,346,952-179,396,566
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 11481
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/55669
- genomic end
- 179394936
- genomic start
- 179347709
- chromosome
- human chromosome 3
- cytogenetic location
- 3q26.33
- expressed in
- canal of the cervix
via Wikidata · CC0
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Encyclopedic overview
2 sectionsContents
- References
- Further reading
Mitofusin-1 is a protein that in humans is encoded by the MFN1 gene.
The protein encoded by this gene is a mediator of mitochondrial fusion. This protein and mitofusin 2 are homologs of the Drosophila protein fuzzy onion (Fzo). They are mitochondrial membrane proteins that interact with each other to facilitate mitochondrial targeting.
Excerpted from Wikipedia’s “MFN1” article, available under the CC BY-SA 4.0 licence.