dynamin
Sign in to saveDynamin is a GTPase protein responsible for endocytosis in the eukaryotic cell. Dynamin is part of the "dynamin superfamily", which includes classical dynamins, dynamin-like proteins, Mx proteins, OPA1, mitofusins, and GBPs. Members of the dynamin family are principally involved in the scission of newly formed vesicles from the membrane of one cellular compartment and their targeting to, and fusion with, another compartment, both at the cell surface (particularly caveolae internalization) as well as at the Golgi apparatus. Dynamin family members also play a role in many processes including div
Key facts
- Protein family.Symbol
- Dynamin_M
- Protein family.Name
- Dynamin central region
- Protein family.image
- PDB 2aka EBI.jpg
- Protein family.caption
- Structure of the nucleotide-free myosin II motor domain from Dictyostelium discoideum fused to the GTPase domain of dynamin I from Rattus norvegicus
- Protein family.Pfam
- PF01031
- Protein family.Pfam_clan
- CL0023
- Protein family.InterPro
- IPR000375
- Protein family.PROSITE
- PDOC00362
via Wikipedia infobox
Article
7 sectionsContents
- Structure
- Function
- Types
- Pharmacology
- Disease implications
- References
- External links
Dynamin is a GTPase protein responsible for endocytosis in the eukaryotic cell. Dynamin is part of the "dynamin superfamily", which includes classical dynamins, dynamin-like proteins, Mx proteins, OPA1, mitofusins, and GBPs. Members of the dynamin family are principally involved in the scission of newly formed vesicles from the membrane of one cellular compartment and their targeting to, and fusion with, another compartment, both at the cell surface (particularly caveolae internalization) as well as at the Golgi apparatus. Dynamin family members also play a role in many processes including division of organelles, cytokinesis and microbial pathogen resistance.
== Structure == thumb|left|Dynamin assembled into helical polymers as visualized by negative stain electron microscopy.|alt=