Monodnaviria
Floreoviria is a realm of eukaryotic viruses that contains all viruses that encode a replication protein that has an N-terminal HUH superfamily endonuclease domain and a C-terminal superfamily 3 helicase domain, as well as all viruses descended from such viruses. Floreovirians typically have circular single-stranded DNA (ssDNA) genomes, but some have linear ssDNA genomes or circular double-stranded DNA (dsDNA) genomes. The prototypical members of the realm are commonly called CRESS-DNA viruses, which stands for circular, Rep-encoding ssDNA viruses. The replication (Rep) protein is involved in
Article
21 sectionsContents
- Classification
- Characteristics
- Genome
- Structure
- Proteins
- Major capsid protein
- Replication-initiator protein
- Replication
- Evolution
- Phylogenetics
- Interactions with hosts
- Disease
- Endogenization
- History
- Etymology
- See also
- Notes
- References
- Books
- Journal articles
- Other
Floreoviria is a realm of eukaryotic viruses that contains all viruses that encode a replication protein that has an N-terminal HUH superfamily endonuclease domain and a C-terminal superfamily 3 helicase domain, as well as all viruses descended from such viruses. Floreovirians typically have circular single-stranded DNA (ssDNA) genomes, but some have linear ssDNA genomes or circular double-stranded DNA (dsDNA) genomes. The prototypical members of the realm are commonly called CRESS-DNA viruses, which stands for circular, Rep-encoding ssDNA viruses. The replication (Rep) protein is involved in initiating replication of viruses in Floreoviria.
Along with the shared replication protein, most floreovirians encode a major capsid protein (MCP) characterized by a single jelly roll motif. The MCP is the primary component of the capsid, a protein shell that surrounds the genome. Floreovirian extracellular bodies (virions) consist of the genome and the capsid, which is icosahedral in shape. Circular ssDNA viruses in the realm replicate through rolling circle replication, and the dsDNA viruses in the realm use bidirectional theta replication. Among linear ssDNA viruses in the realm, parvoviruses use rolling hairpin replication, whereas bidnaviruses encode a protein-primed DNA polymerase that performs replication.