MRPS25

Name

mitochondrial ribosomal protein S25

Type

protein-coding

Position

15,009,611–15,065,339 (−)

Aliases

COXPD50, MRP-S25, RPMS25, mS25

Ensembl

ENSG00000131368

RefSeq RNA

NM_022497.5, NR_135246.2, NR_135247.2

RefSeq protein

NP_071942.1

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein. A pseudogene corresponding to this gene is found on chromosome 4. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016].

via MyGene.info

Gene · Ensembl

mitochondrial ribosomal protein S25

Symbol

MRPS25

Biotype

Protein coding

Organism

Homo sapiens

Location

3:15,009,611-15,065,339

Strand

Reverse (−)

Assembly

GRCh38

Wikidata facts

Instance of

gene

via Wikidata · CC0