File:MS_Demyelinisation_CD68_10xv2.jpg · Wikimedia Commons · See Wikimedia Commons
多发性硬化症
Sign in to saveAlso known as MS, encephalomyelitis disseminata, insular sclerosis, disseminated sclerosis, generalized multiple sclerosis
disease that damages the myelin sheaths around nerve axons
Multiple sclerosis is a disease where the body's immune system damages the protective coating (called myelin) around nerve fibers, which disrupts communication between the brain and the rest of the body. It matters because this damage can lead to a range of physical and cognitive symptoms that affect a person's ability to move, see, and think clearly.
AI-generated from the Wikipedia summary — may contain errors.
Research
127,009 papers- Progressive multiple sclerosis: from pathogenic mechanisms to treatment.ReviewBrain : a journal of neurology · 2017Correale J, Gaitán MI, Ysrraelit MC et al.DOI: 10.1093/brain/aww258
- Multiple sclerosis.Biomedical journal · 2014Wei FCDOI: 10.4103/2319-4170.130317
- Multiple sclerosis under the spotlight.The Lancet. Neurology · 2021The Lancet NeurologyDOI: 10.1016/S1474-4422(21)00170-8
- Multiple sclerosis.Nature · 2016Owens BDOI: 10.1038/540S1a
- Pediatric Multiple Sclerosis: A Review.ReviewAdvances in pediatrics · 2019Langille MM, Rutatangwa A, Francisco CDOI: 10.1016/j.yapd.2019.03.003
- Pathophysiology, Diagnosis, Treatment and Emerging Neurotherapeutic Targets for Progressive Multiple Sclerosis: The Age of PIRA.ReviewNeurologic clinics · 2024Carlson AK, Fox RJDOI: 10.1016/j.ncl.2023.07.002
- Multiple sclerosis.Nature · 2012Brody HDOI: 10.1038/nature11104
- Multiple Sclerosis: Basic and Clinical.ReviewAdvances in neurobiology · 2017Buzzard K, Chan WH, Kilpatrick T et al.DOI: 10.1007/978-3-319-57193-5_8
via PubMed
Wikidata facts
- Instance of
- symptom or sign
- Subclass of
- disease
- Image
- MS Demyelinisation CD68 10xv2.jpg
Show 15 more facts
- topic's main category
- Category:Multiple sclerosis
- Commons category
- Multiple sclerosis
- discoverer or inventor
- Jean-Martin Charcot
- NCI Thesaurus ID
- C3243
- medical examination
- lumbar puncture
- health specialty
- neurology
- ICPC 2 ID
- N86
- drug or therapy used for treatment
- ocrelizumab
- topic has template
- Template:Demyelinating diseases of CNS
- ICD-9-CM
- 340
- external data available at URL
- www.nanbyou.or.jp/entry/3806
- different from
- sclerosis
- prevalence
- 0.001671
- on focus list of Wikimedia project
- Wikipedia:Vital articles/Level/4
- exact match
- id.nlm.nih.gov/mesh/D009103
Sources (12)
via Wikidata · CC0
Article · 中文
多發性硬化症(英語:Multiple sclerosis,縮寫:MS)是一種,患者腦或脊髓中的神經細胞表面的絕緣物質(即髓鞘)受到破壞,神經系統的訊息傳遞受損,導致一系列可能發生的症狀,影響患者的活動、心智、甚至精神狀態。這些症狀可能包括複視、單側視力受損、肌肉無力、感覺遲鈍,或協調障礙。多發性硬化症的病情多變,患者的症狀可能反覆發作,也可能持續加劇。在每次發作之間,症狀有可能完全消失,但永久性的神經損傷仍然存在,這在病情嚴重的患者特別明顯。 雖然具體的成因不明,但多發性硬化症的機制可能為髓鞘受到免疫系統破壞或生成髓鞘的細胞發生問題,可能的原因包括遺傳與環境因素,例如受病毒感染的刺激而引發自體免疫反應。多發性硬化症的診斷需藉助臨床表現和相關的影像學證據支持。 目前尚無根治多發性硬化症的方法,現有的治療多為改善患者發作後的日常功能,並預防疾病再度復發。物理治療則能改善患者的功能。許多人會尋求替代疗法,儘管其療效缺乏證據支持。多發性硬化症的長期預後很難預測,通常女性、較年輕發作、反覆復發緩解(relapsing-remitting)和一開始發作次數較少的患者有較佳的預後。患者的預期壽命較一般人少5至10年。 多發性硬化症是最常見的中樞神經系統。2015年全球約有230萬人罹患此病,但不同地區和族群的盛行率差異極大;同年,約有18,900人死於多發性硬化症,相較於1990年的12,000人高出許多。多發性硬化症通常在20到50歲之間發病,女性的發生率為男性的2倍。1868年,让-马丁·沙可首次描述了多發性硬化症,意指大腦白質和脊髓中有許多疤痕(sclerae,可理解為現在所稱的斑塊或病灶)。多種新的治療與診斷方法都正在研究當中。
Abstract from DBpedia / Wikipedia · CC BY-SA
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