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Also known as genetic mutation, gene mutation, mutations, genetic mutations, gene mutations, genetic change, genetic changes

thumb|Three major single-chromosome mutations: deletion (genetics)|deletion (1), duplication (2) and inversion (3).

AI overview

A mutation is a change in an organism's genetic material, such as when a section of DNA is deleted, copied extra times, or flipped around. Mutations matter because they create genetic variation in populations, which can lead to evolution, disease, or sometimes have no noticeable effect at all.

AI-generated from the Wikipedia summary — may contain errors.

Research

1,395,250 papers

Mutation bias and adaptation in bacteria.ReviewMicrobiology (Reading, England) · 2023Horton JS, Taylor TBDOI: 10.1099/mic.0.001404
Genomic instability--an evolving hallmark of cancer.ReviewNature reviews. Molecular cell biology · 2010Negrini S, Gorgoulis VG, Halazonetis TDDOI: 10.1038/nrm2858
Distribution of mutation rates challenges evolutionary predictability.Microbiology (Reading, England) · 2023Sun TA, Lind PADOI: 10.1099/mic.0.001323
Genetic basis of a spontaneous mutation's expressivity.Genetics · 2022Schell R, Hale JJ, Mullis MN et al.DOI: 10.1093/genetics/iyac013
Phenotype switching of the mutation rate facilitates adaptive evolution.Genetics · 2023Lobinska G, Pilpel Y, Ram YDOI: 10.1093/genetics/iyad111
Mutation bias and GC content shape antimutator invasions.Nature communications · 2019Couce A, Tenaillon ODOI: 10.1038/s41467-019-11217-6
Sequence dependencies and mutation rates of localized mutational processes in cancer.Genome medicine · 2023Poulsgaard GA, Sørensen SG, Juul RI et al.DOI: 10.1186/s13073-023-01217-z
PIK3CA Mutation in HPV-Associated OPSCC Patients Receiving Deintensified Chemoradiation.Journal of the National Cancer Institute · 2020Beaty BT, Moon DH, Shen CJ et al.DOI: 10.1093/jnci/djz224

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