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nephrotoxicity

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Also known as drug-induced kidney injury, toxic nephropaty, Nephropathy toxic

Nephrotoxicity is toxicity in the kidneys. It is a poisonous effect of some substances, both toxic chemicals and medications, on kidney function. There are various forms, and some drugs may affect kidney function in more than one way. Nephrotoxins are substances displaying nephrotoxicity.

~9 min read

Article

17 sections
Contents
  • Types of toxicity
  • Cardiovascular
  • Direct tubular effect
  • Acute interstitial nephritis
  • Chronic interstitial nephritis
  • Acute glomerulonephritis
  • Causes of diabetes insipidus
  • Other nephrotoxins
  • Diagnosis
  • Nephrotoxicity in the medical workplace
  • Occupational exposure
  • Chemical mechanisms in Nephrotoxicity
  • Prevention and control
  • Etymology
  • See also
  • References
  • Further reading

Nephrotoxicity is toxicity in the kidneys. It is a poisonous effect of some substances, both toxic chemicals and medications, on kidney function. There are various forms, and some drugs may affect kidney function in more than one way. Nephrotoxins are substances displaying nephrotoxicity.

Nephrotoxicity should not be confused with some medications predominantly excreted by the kidneys needing their dose adjusted for the decreased kidney function (e.g., heparin, lithium).

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