furosemide

Also known as dihydroflumethiazide, methforylthiazidine, 4-chloro-N-(2-furylmethyl)-5-sulfamoylanthranilic acid, 4-chloro-N-furfuryl-5-sulfamoylanthranilic acid, 2-furfurylamino-4-chloro-5-sulfamoylbenzoic acid, 4-chloro-5-sulfamoyl-N-furfuryl-anthranilic acid

Furosemide, sold under the brand name Lasix among others, is a loop diuretic medication used to treat edema due to heart failure, liver scarring, or kidney disease. Furosemide may also be used for the treatment of high blood pressure. It can be taken intravenously or orally. When given intravenously, furosemide typically takes effect within five minutes; when taken orally, it typically metabolizes within an hour.

Key facts

Drug.ChEBI: 47426
Drug.ChEMBL: 35
Drug.Watchedfields: changed
Drug.verifiedrevid: 461114978
Drug.image: Furosemide.svg
Drug.image_class: skin-invert-image
Drug.image2: Furosemide-1Z9Y-3D-balls.png
Drug.image_class2: bg-transparent
Drug.tradename: Lasix, Furoscix, others
Drug.MedlinePlus: a682858
Drug.DailyMedID: Furosemide
Drug.pregnancy_AU: C
Drug.routes_of_administration

~14 min read

Article

13 sections

Contents

Medical uses
Kidney disease
Other information
Adverse effects
Interactions
Mechanism of action
Pharmacokinetics
Names
Veterinary uses
Horses
References
Further reading
External links

Common side effects include orthostatic hypotension (decrease in blood pressure while standing, and associated lightheadedness), tinnitus (ringing in the ears), and photosensitivity (sensitivity to light). Potentially serious side effects include electrolyte abnormalities, low blood pressure, and hearing loss. It is recommended that serum electrolytes (especially potassium), serum carbon dioxide|, creatinine, BUN levels, and liver and kidney functioning be monitored in patients taking furosemide. It is also recommended to be alert for the occurrence of any potential blood dyscrasias.