nedaplatin
Sign in to saveNedaplatin, sold in Japan as Aqupla (see External Links), is a platinum-based chemotherapy agent. It is toxic to DNA, causing damage to DNA, limiting DNA repair and ultimately limiting DNA synthesis, limiting the propagation of cancer cells.
Research
955 papers- [Nedaplatin].Gan to kagaku ryoho. Cancer & chemotherapy · 1996
- Hypersensitivity reaction to nedaplatin: A case report and literature review.Medicine · 2023
- Comparison of nedaplatin-based versus cisplatin-based chemotherapy for advanced non-small cell lung cancer among East Asian populations: A meta-analysis.Scientific reports · 2015
- Nedaplatin use in patients with hypersensitivity reaction episodes to carboplatin.Taiwanese journal of obstetrics & gynecology · 2020
- Neoadjuvant camrelizumab combined with paclitaxel and nedaplatin for locally advanced esophageal squamous cell carcinoma: a single-arm phase 2 study (cohort study).International journal of surgery (London, England) · 2024
via PubMed
Wikidata facts
- Mass
- 305.033933
Show 2 more facts
- chemical formula
- C₂H₁₀N₂O₃Pt
- canonical SMILES
- C(C(=O)O)O.N.N.[Pt]
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~8 min read
Article
14 sectionsContents
- Medical uses
- Available forms
- Adverse effects
- Toxicity
- Pharmacology
- Mechanism of action
- Pharmacokinetics
- Chemistry
- Structure
- Reactivity
- Synthesis
- History
- References
- External links
Nedaplatin, sold in Japan as Aqupla (see External Links), is a platinum-based chemotherapy agent. It is toxic to DNA, causing damage to DNA, limiting DNA repair and ultimately limiting DNA synthesis, limiting the propagation of cancer cells.
== Medical uses == Nedaplatin can be prescribed to patients with the following types of cancer: small/non-small cell lung cancer oesophageal cancer uterine cervical cancer urothelial cancer testicular cancer ovarian cancer prostate cancer head and neck cancer
Available in 9 languages
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