File:Sarin_Wirkungsweise.png · Wikimedia Commons · See Wikimedia Commons
nerve agent
Sign in to saveAlso known as nerve agents
class of organophosphates; classified as weapons of mass destruction
Research
57,885 papers- Organophosphorus nerve agent poisoning: managing the poisoned patient.British journal of anaesthesia · 2019
- Human butyrylcholinesterase efficacy against nerve agent exposure.Journal of biochemical and molecular toxicology · 2017
- Use of a Nerve Agent Antidote-Dosing Tool for Mass Casualty Incident Emergency Preparedness.Disaster medicine and public health preparedness · 2023
- Diagnostics and treatment of nerve agent poisoning-current status and future developments.Annals of the New York Academy of Sciences · 2020
- Novichok nerve agent poisoning.Lancet (London, England) · 2021
via PubMed
~38 min read
Encyclopedic overview
Nerve agents act in the neuromuscular junction. Sarin (red) inhibits the function of acetylcholinesterase (yellow), preventing breakdown of acetylcholine (blue). Acetylcholine buildup causes continuous nerve impulses.
Pulmonary/choking
Excerpted from Wikipedia’s “nerve agent” article, available under the CC BY-SA 4.0 licence.