NOB1
Sign in to saveAlso known as ART-4, MST158, NOB1P, PSMD8BP1, MSTP158, NIN1/PSMD8 binding protein 1 homolog, NIN1 (RPN12) binding protein 1 homolog
RNA-binding protein NOB1 is a protein that in humans is encoded by the NOB1 gene.
Gene data
NOB1- Name
- NIN1 (RPN12) binding protein 1 homolog
- Type
- protein-coding
- Aliases
- ART-4, MST158, MSTP158, NOB1P, PSMD8BP1
In yeast, over 200 protein and RNA cofactors are required for ribosome assembly, and these are generally conserved in eukaryotes. These factors orchestrate modification and cleavage of the initial 35S precursor rRNA transcript into the mature 18S, 5.8S, and 25S rRNAs, folding of the rRNA, and binding of ribosomal proteins and 5S RNA. Nob1 is involved in pre-rRNA processing. In a late cytoplasmic processing step, Nob1 cleaves a 20S rRNA intermediate at cleavage site D to produce the mature 18S rRNA (Lamanna and Karbstein, 2009 [PubMed 19706509]).[supplied by OMIM, Nov 2010].
via MyGene.info
Wikidata facts
- Image
- Protein NOB1 PDB 2con.png
Show 5 more facts
- HomoloGene ID
- 31924
- exact match
- identifiers.org/ncbigene/28987
- genomic end
- 69754926
- genomic start
- 69741871
- cytogenetic location
- 16q22.1
Sources (4)
via Wikidata · CC0
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Article
2 sectionsContents
- References
- Further reading
RNA-binding protein NOB1 is a protein that in humans is encoded by the NOB1 gene.
==References==