Structure via PubChem · Public domain (PubChem)
norgestrienone
Sign in to saveNorgestrienone, sold under the brand names Ogyline, Planor, and Miniplanor, is a progestin medication which has been used in birth control pills, sometimes in combination with ethinylestradiol. It was developed by Roussel Uclaf and has been registered for use only in France. Under the brand name Planor, it has been marketed in France as 2 mg norgestrienone and 50 μg ethinylestradiol tablets. It is taken by mouth.
Chemical data
- Formula
- C20H22O2
- Molecular weight
- 294.4 g/mol
- IUPAC name
- (8S,13S,14S,17R)-17-ethynyl-17-hydroxy-13-methyl-1,2,6,7,8,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
- SMILES
- C[C@]12C=CC3=C4CCC(=O)C=C4CC[C@H]3[C@@H]1CC[C@]2(C#C)O
- InChIKey
- GVDMJXQHPUYPHP-FYQPLNBISA-N
- XLogP
- 1.8
- Polar surface area
- 37.3 Ų
- H-bond donors
- 1
- H-bond acceptors
- 2
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
via ChEMBL · EBI
Research
264 papers- Endometriosis.British journal of hospital medicine · 1988
- [Antiprogestins].Zentralblatt fur Gynakologie · 1988
- Endometriosis.Lancet (London, England) · 1993
- Treatment of endometriosis.Lancet (London, England) · 1992
- Endometriosis: medical therapy.Bailliere's clinical obstetrics and gynaecology · 1993
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 294.162
Show 4 more facts
- chemical formula
- C₂₀H₂₂O₂
- canonical SMILES
- CC12C=CC3=C4CCC(=O)C=C4CCC3C1CCC2(C#C)O
- isomeric SMILES
- C[C@]12C=CC3=C4CCC(=O)C=C4CC[C@H]3[C@@H]1CC[C@]2(C#C)O
- Commons category
- Norgestrienone
Sources (2)
via Wikidata · CC0
~4 min read
Encyclopedic overview
13 sectionsContents
- Medical uses
- Side effects
- Pharmacology
- Pharmacodynamics
- Pharmacokinetics
- Chemistry
- History
- Society and culture
- Generic names
- Brand names
- Availability
- Research
- References
Norgestrienone, sold under the brand names Ogyline, Planor, and Miniplanor, is a progestin medication which has been used in birth control pills, sometimes in combination with ethinylestradiol. It was developed by Roussel Uclaf and has been registered for use only in France. Under the brand name Planor, it has been marketed in France as 2 mg norgestrienone and 50 μg ethinylestradiol tablets. It is taken by mouth.
Norgestrienone is a progestin, or a synthetic progestogen, and hence is an agonist of the progesterone receptor, the biological target of progestogens like progesterone. It has some androgenic activity.
Excerpted from Wikipedia’s “norgestrienone” article, available under the CC BY-SA 4.0 licence.