NPM3

Also known as PORMIN, TMEM123, nucleophosmin/nucleoplasmin 3

Nucleoplasmin-3 is a protein that in humans is encoded by the NPM3 gene.

In the Vinony graph

Vinony's link graph records 3 inbound references to NPM3, and connects out to PubMed, human chromosome 10 and Ensembl genome database project.

It is catalogued under the topic Genes on human chromosome 10.

Vinony links it to 6 Wikipedia language editions.

Gene data

NPM3

Name: nucleophosmin/nucleoplasmin 3
Type: protein-coding
Position: 101,781,318–101,783,446 (−)
Aliases: PORMIN
Ensembl: ENSG00000107833
RefSeq RNA: NM_006993.3
RefSeq protein: NP_008924.1

The protein encoded by this gene is related to the nuclear chaperone phosphoproteins, nucleoplasmin and nucleophosmin. This protein is strongly expressed in diverse cell types where it localizes primarily to the nucleus. Based on its similarity to nucleoplasmin and nucleophosmin, this protein likely functions as a molecular chaperone in the cell nucleus. [provided by RefSeq, Oct 2008].

Gene Ontology

Biological process

chromatin remodeling

Molecular function

chromatin binding RNA binding RNA binding protein binding histone binding

Cellular component

nucleus nucleoplasm nucleolus nucleolus cytoplasm

via MyGene.info

Gene · Ensembl

nucleophosmin/nucleoplasmin 3

Symbol: NPM3
Biotype: Protein coding
Organism: Homo sapiens
Location: 10:101,781,318-101,783,446
Strand: Reverse (−)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of: gene

Show 7 more facts

HomoloGene ID: 5083
found in taxon: Homo sapiens
exact match: identifiers.org/ncbigene/10360
genomic end: 103543170
genomic start: 103541082
chromosome: human chromosome 10
cytogenetic location: 10q24.32

Sources (4)

via Wikidata · CC0

~1 min read

Encyclopedic overview

3 sections

Contents

References
Further reading
External links

Nucleoplasmin-3 is a protein that in humans is encoded by the NPM3 gene.

The protein encoded by this gene is related to the nuclear chaperone phosphoproteins, nucleoplasmin and nucleophosmin. It is highly homologous to the murine Npm3 gene. Based on the structural similarity of the human NPM3 gene product to nucleoplasmin and nucleophosmin, NPM3 may represent a new member of this gene family, and may share basic functions with the molecular chaperones.

Excerpted from Wikipedia’s “NPM3” article, available under the CC BY-SA 4.0 licence.