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EntityQ40260· pop 105· linked from 2,582 articles

细胞核

Also known as GO:0005634, cell nuclei, nuclei, cell nucleus

membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated

AI overview

The nucleus is a structure inside cells that acts like a control center, holding the chromosomes that contain your genetic instructions. It's essential because it's where your DNA is kept safe and copied so cells can divide and your body can grow and function properly.

AI-generated from the Wikipedia summary — may contain errors.

Research

540,613 papers

The Material Properties of the Cell Nucleus: A Matter of Scale.ReviewCells · 2023Hertzog M, Erdel FDOI: 10.3390/cells12151958
The Neutrophil Nucleus and Its Role in Neutrophilic Function.ReviewJournal of cellular biochemistry · 2015Carvalho LO, Aquino EN, Neves AC et al.DOI: 10.1002/jcb.25124
The cell nucleus.ReviewExperimental cell research · 2004Wieslander LDOI: 10.1016/j.yexcr.2004.03.003
Has translation in the nucleus found its purpose?Nature reviews. Molecular cell biology · 2024Fåhraeus RDOI: 10.1038/s41580-023-00651-6
Exporting RNA from the nucleus to the cytoplasm.ReviewNature reviews. Molecular cell biology · 2007Köhler A, Hurt EDOI: 10.1038/nrm2255
Origin of the cell nucleus.ReviewBioEssays : news and reviews in molecular, cellular and developmental biology · 1988Cavalier-Smith TDOI: 10.1002/bies.950090209
The role of physicochemical processes in the formation of the 3D genome and compartmentalization of the cell nucleus.ReviewPostepy biochemii · 2024Razin SVDOI: 10.18388/pb.2021_512
Chromatin organization in the mammalian nucleus.ReviewInternational review of cytology · 2005Gilbert N, Gilchrist S, Bickmore WADOI: 10.1016/S0074-7696(04)42007-5

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Wikidata facts

Part of: eukaryotic cell
Image: Cell nucleus 1 -- Smart-Servier.png

Show 8 more facts

Commons category: Cell nucleus
topic's main category: Category:Cell nucleus
exact match: purl.obolibrary.org/obo/GO_0005634
physically interacts with: anti-nuclear antibody
NCI Thesaurus ID: C13197
studied by: karyology
different from: atomic nucleus
topic has template: Template:Nucleus

Sources (5)

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Article · 中文

细胞核（拉丁語：nucleus）是真核細胞特有的细胞结构，是真核细胞重要的组成部分，是一种封閉式膜狀细胞器。细胞核內部含有細胞中绝大多數的遺傳物質，就是DNA。這些DNA與多種蛋白質（組織蛋白和非组织蛋白）、少量的mRNA等複合形成染色質，而染色質在細胞分裂時，會被压缩，形成染色體，其中所含的所有基因合稱為核基因組。細胞核的作用，是維持基因的完整性，並藉由調節基因表現來影響細胞活動。細胞核的主要構造為核膜，是一種將細胞核完全包覆的雙層膜，使膜內物質與細胞質、以及具有細胞骨架功能的網狀結構核纖層分隔開來。由於多數分子無法直接穿透核膜，因此核膜上存在一些位点上融合形成环状开口，即核孔，作為物質的進出通道。這些孔洞可讓小分子與自由通透；而如蛋白質般較大的分子，則需要攜帶蛋白的幫助才能通過。核運輸是細胞中最重要的功能；基因表現與染色體的保存，皆有賴於核孔上所進行的輸送作用。細胞核內不含有任何其他膜狀的結構，但也並非完全均勻，其中存在許多由特殊蛋白質、RNA以及DNA所複合而成的次核體。而其中受理解最透徹的是核仁，此結構主要參與核糖體的合成、加工和成熟，以及核糖体亚单位的组装。核糖體在核仁中產出之後，會進入細胞質進行mRNA的轉譯。

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