File:Chromatin_Structures.png · Wikimedia Commons · See Wikimedia Commons
chromatin
Sign in to saveAlso known as GO:0000785
thumb|358x358px|The major structures in DNA compaction: DNA, the [[nucleosome, the 11 nm beads on a string chromatin fibre and the metaphase chromosome.]]
Chromatin is the material made of DNA wound tightly around proteins, which allows the long strands of DNA to fit inside cells and be organized into a compact form. It matters because this packaging system controls which genes are accessible and active in a cell, influencing how cells function and develop.
AI-generated from the Wikipedia summary — may contain errors.
Research
168,959 papers- Chromatin control of human cytomegalovirus infection.ReviewmBio · 2023Matthews SM, Groves IJ, O'Connor CMDOI: 10.1128/mbio.00326-23
- Chromatin's physical properties shape the nucleus and its functions.ReviewCurrent opinion in cell biology · 2019Stephens AD, Banigan EJ, Marko JFDOI: 10.1016/j.ceb.2019.02.006
- Linking chromatin acylation mark-defined proteome and genome in living cells.Cell · 2023Qin F, Li B, Wang H et al.DOI: 10.1016/j.cell.2023.02.007
- Progresses in the plant 3D chromatin architecture.ReviewYi chuan = Hereditas · 2020Dong QL, Wang JB, Li XC et al.DOI: 10.16288/j.yczz.19-326
- Chromatin-mediated epigenetic regulation of HSV-1 transcription as a potential target in antiviral therapy.ReviewAntiviral research · 2021Schang LM, Hu M, Cortes EF et al.DOI: 10.1016/j.antiviral.2021.105103
- Nucleosomes unwrapped: Structural perspectives on transcription through chromatin.ReviewCurrent opinion in structural biology · 2023Farnung LDOI: 10.1016/j.sbi.2023.102690
- Customizing Host Chromatin: a Bacterial Tale.ReviewMicrobiology spectrum · 2019Connor M, Arbibe L, Hamon MDOI: 10.1128/microbiolspec.BAI-0015-2019
- Three-Dimensional Chromatin Structure of the EBV Genome: A Crucial Factor in Viral Infection.ReviewViruses · 2023Caruso LB, Maestri D, Tempera IDOI: 10.3390/v15051088
via PubMed
Wikidata facts
- Image
- 30nm Chromatin Structures.png
Show 2 more facts
- Commons category
- Chromatin
- exact match
- purl.obolibrary.org/obo/GO_0000785
via Wikidata · CC0
~26 min read
Article
27 sectionsContents
- Basic chromatin structure
- Nucleosomes
- Historical 30-nm fiber model
- Three-dimensional genome organization
- Chromatin loops
- TADs
- Chromatin compartments
- Chromosome territories
- Chromatin dynamics and regulation
- Histone modifications
- Chromatin remodeling
- Transcriptional bursting
- Structure of DNA
- Chromatin during the cell cycle
- Spatial organization of chromatin in the cell nucleus
- Cell-cycle dependent structural organization
- Specialized chromatin states
- Sperm chromatin
- Chromatin and DNA repair
- Methods to study chromatin
- Physical and topological properties
- Chromatin knots
- See also
- Notes
- References
- Additional sources
- External links
thumb|358x358px|The major structures in DNA compaction: DNA, the [[nucleosome, the 11 nm beads on a string chromatin fibre and the metaphase chromosome.]]
Chromatin is a complex of DNA and protein responsible for condensing and packaging chromosomal DNA. Chromatin is found in both bacterial and eukaryotic cells.This article deals almost exclusively with eukaryotic chromatin.