chromatin
Sign in to savethumb|358x358px|The major structures in DNA compaction: DNA, the [[nucleosome, the 11 nm beads on a string chromatin fibre and the metaphase chromosome.]]
AI overview
Chromatin is the material made of DNA wound tightly around proteins, which allows the long strands of DNA to fit inside cells and be organized into a compact form. It matters because this packaging system controls which genes are accessible and active in a cell, influencing how cells function and develop.
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Article
27 sectionsContents
- Basic chromatin structure
- Nucleosomes
- Historical 30-nm fiber model
- Three-dimensional genome organization
- Chromatin loops
- TADs
- Chromatin compartments
- Chromosome territories
- Chromatin dynamics and regulation
- Histone modifications
- Chromatin remodeling
- Transcriptional bursting
- Structure of DNA
- Chromatin during the cell cycle
- Spatial organization of chromatin in the cell nucleus
- Cell-cycle dependent structural organization
- Specialized chromatin states
- Sperm chromatin
- Chromatin and DNA repair
- Methods to study chromatin
- Physical and topological properties
- Chromatin knots
- See also
- Notes
- References
- Additional sources
- External links
thumb|358x358px|The major structures in DNA compaction: DNA, the [[nucleosome, the 11 nm beads on a string chromatin fibre and the metaphase chromosome.]]
Chromatin is a complex of DNA and protein responsible for condensing and packaging chromosomal DNA. Chromatin is found in both bacterial and eukaryotic cells.This article deals almost exclusively with eukaryotic chromatin.