ohmefentanyl
Sign in to saveOhmefentanyl (also known as β-hydroxy-3-methylfentanyl, OMF and RTI-4614-4) is an extremely potent opioid analgesic drug which selectively binds to the μ-opioid receptor.
Key facts
- Drug.Watchedfields
- changed
- Drug.verifiedrevid
- 447755463
- Drug.IUPAC_name
- N-[1-(2-hydroxy-2-phenylethyl)-3-methylpiperidin-4-yl]-N-phenylpropanamide
- Drug.image
- Ohmefentanyl.svg
- Drug.image_class
- skin-invert-image
- Drug.width
- 220px
- Drug.image2
- Ohmyfentanyl 3D Ball and Stick.png
- Drug.image_class2
- bg-transparent
- Drug.width2
- 220px
- Drug.legal_BR
- F1
- Drug.legal_CA
- Schedule I
- Drug.legal_US
- Schedule I
- Drug.legal_UK
- Class A
- Drug.legal_DE
- Anlage I
- Drug.legal_UN
- P I
- Drug.CAS_number
- 78995-14-9
- Drug.ATC_prefix
- none
- Drug.PubChem
- 62279
via Wikipedia infobox
Article
4 sectionsContents
- Synthesis
- See also
- References
- External links
Ohmefentanyl (also known as β-hydroxy-3-methylfentanyl, OMF and RTI-4614-4) is an extremely potent opioid analgesic drug which selectively binds to the μ-opioid receptor.
There are eight possible stereoisomers of ohmefentanyl. These stereoisomers are among the most potent μ-opioid receptor agonists known, comparable to super-potent opioids such as carfentanil and etorphine which are only legally used for tranquilizing large animals such as elephants in veterinary medicine. In mouse studies, the most active stereoisomer, 3R,4S,βS-ohmefentanyl, was 28 times more powerful as a painkiller than fentanyl, the chemical from which it is derived, and 6300 times more powerful than morphine. Ohmefentanyl has three stereogenic centers and eight stereoisomers, which are named F9201–F9208. Researchers are studying the different pharmaceutical properties of these isomers.