3-methylfentanyl
3-Methylfentanyl (3-MF, mefentanyl) is an opioid analgesic that is an analog of fentanyl. 3-Methylfentanyl is one of the most potent opioids, estimated to be between 400 and 6000 times stronger than morphine, depending on which isomer is used (with the cis isomers being the more potent ones).
Chemical data
- Formula
- C23H30N2O
- Molecular weight
- 350.5 g/mol
- IUPAC name
- N-[3-methyl-1-(2-phenylethyl)piperidin-4-yl]-N-phenylpropanamide
via PubChem
Research
85 papers- Pharmacological effect of (±)-trans-3-methylfentanyl and (±)-cis-3-methylfentanyl.Psychopharmacology · 2026
- Analysis of cis and trans 3-methylfentanyl by liquid chromatography-high resolution mass spectrometry and findings in forensic toxicology casework.Drug testing and analysis · 2018
- (+)-cis-3-methylfentanyl and its analogs bind pseudoirreversibly to the mu opioid binding site: evidence for pseudoallosteric modulation.Neuropharmacology · 1991
- Blood levels of 3-methylfentanyl in 3 fatal poisoning cases.The American journal of forensic medicine and pathology · 2006
- Interaction models of 3-methylfentanyl derivatives with mu opioid receptors.
Article
5 sectionsContents
- Overview and history
- Use as chemical weapon
- Synthesis
- See also
- References
3-Methylfentanyl (3-MF, mefentanyl) is an opioid analgesic that is an analog of fentanyl. 3-Methylfentanyl is one of the most potent opioids, estimated to be between 400 and 6000 times stronger than morphine, depending on which isomer is used (with the cis isomers being the more potent ones).
== Overview and history ==