Structure via PubChem · Public domain (PubChem)
olaflur
Sign in to saveOlaflur (INN, or amine fluoride 297) is a fluoride-containing substance that is an ingredient of toothpastes and solutions for the prevention of dental caries. It has been in use since 1966. Especially in combination with dectaflur, it is also used in the form of gels for the treatment of early stages of caries, sensitive teeth, and by dentists for the refluoridation of damaged tooth enamel.
Chemical data
- Formula
- C27H60F2N2O3
- Molecular weight
- 498.8 g/mol
- IUPAC name
- 2-[3-[bis(2-hydroxyethyl)amino]propyl-octadecylamino]ethanol;dihydrofluoride
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
via ChEMBL · EBI
Research
152 papers- Allergic contact cheilitis caused by olaflur in toothpaste.Contact dermatitis · 2017
- Effects of two fluoridation measures on erosion progression in human enamel and dentine in situ.Caries research · 2004
- Effectiveness of two fluoridation measures on erosion progression in human enamel and dentine in vitro.Caries research · 2001
- Salivary Flow Rate During Toothbrushing.Oral health & preventive dentistry · 2022
- Evaluation of Local Tolerance of Structurally Different Olaflur Compounds.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association · 2026
via PubMed
~4 min read
Encyclopedic overview
6 sectionsContents
- Overdosage
- Interactions
- Chemistry and mechanism of action
- Synthesis
- See also
- References
{{Drugbox | Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 447933354 | IUPAC_name = ''N,N,N'-tris(2-hydroxyethyl)-N-octadecylpropane-1,3-diamine dihydrofluoride | image = Olaflur2.png | image_class = skin-invert-image | width = 300
| tradename = | Drugs.com = | pregnancy_AU = | pregnancy_US = | pregnancy_category = No adequate studies | legal_AU = | legal_CA = | legal_UK = | legal_US = | legal_status = OTC | routes_of_administration = Topical (toothpaste, mouthwash, gel)
Excerpted from Wikipedia’s “olaflur” article, available under the CC BY-SA 4.0 licence.
Gallery (2)
Available in 11 languages
via Wikidata sitelinks · CC0