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dectaflur
Sign in to saveDectaflur (INN) is a fluoride-containing substance used for the prevention and treatment of dental caries, sensitive teeth, and the refluoridation of damaged tooth enamel, typically in combination with olaflur.
Chemical data
- Formula
- C18H38FN
- Molecular weight
- 287.5 g/mol
- IUPAC name
- (E)-octadec-9-en-1-amine;hydrofluoride
- SMILES
- CCCCCCCC/C=C/CCCCCCCCN.F
- InChIKey
- QGSCPWWHMSCFOV-RRABGKBLSA-N
- Polar surface area
- 26 Ų
- H-bond donors
- 2
- H-bond acceptors
- 2
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
via ChEMBL · EBI
Wikidata facts
- Mass
- 287.298828
Show 3 more facts
- chemical formula
- C₁₈H₃₈FN
- canonical SMILES
- CCCCCCCCC=CCCCCCCCCN.F
- isomeric SMILES
- CCCCCCCC/C=C/CCCCCCCCN.F
Sources (1)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- Chemistry and mechanism of action
- Side effects
- References
Dectaflur (INN) is a fluoride-containing substance used for the prevention and treatment of dental caries, sensitive teeth, and the refluoridation of damaged tooth enamel, typically in combination with olaflur.
==Chemistry and mechanism of action== Dectaflur consists of oleyl amine (the amine corresponding to oleyl alcohol) and hydrofluoric acid. Oleyl amine with its long lipophilic hydrocarbon chain has surfactant properties. It forms a film layer on the surface of teeth, which facilitates incorporation of fluoride into the top layers of the enamel, reaching a depth of only a few nanometers. The precise mechanism of action is unknown.
Excerpted from Wikipedia’s “dectaflur” article, available under the CC BY-SA 4.0 licence.