PALB2
Sign in to saveAlso known as FANCN, PNCA3, partner and localizer of BRCA2
Partner and localizer of BRCA2, also known as PALB2 or FANCN, is a protein which in humans is encoded by the PALB2 gene.
Gene data
PALB2- Name
- partner and localizer of BRCA2
- Type
- protein-coding
- Position
- 23,603,158–23,641,342 (−)
- Aliases
- BROVCA5, FANCN, PNCA3
- Ensembl
- ENSG00000083093
- RefSeq RNA
- NM_001407296.1, NM_001407297.1, NM_001407298.1, NM_001407299.1, NM_001407300.1
- RefSeq protein
- NP_001394225.1, NP_001394226.1, NP_001394227.1, NP_001394228.1, NP_001394229.1
This gene encodes a protein that may function in tumor suppression. This protein binds to and colocalizes with the breast cancer 2 early onset protein (BRCA2) in nuclear foci and likely permits the stable intranuclear localization and accumulation of BRCA2. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
partner and localizer of BRCA2
- Symbol
- PALB2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 16:23,603,158-23,641,342
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- PALB2 BRCA2.png
Show 8 more facts
- HomoloGene ID
- 11652
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/79728
- genomic end
- 23652631
- genomic start
- 23614488
- chromosome
- human chromosome 16
- cytogenetic location
- 16p12.2
- genetic association
- urogenital neoplasm
Sources (7)
via Wikidata · CC0
~4 min read
Encyclopedic overview
7 sectionsContents
- Function
- Clinical significance
- Meiosis
- See also
- References
- Further reading
- External links
Partner and localizer of BRCA2, also known as PALB2 or FANCN, is a protein which in humans is encoded by the PALB2 gene.
== Function ==
Excerpted from Wikipedia’s “PALB2” article, available under the CC BY-SA 4.0 licence.