PAX4
Sign in to saveAlso known as KPD, MODY9, paired box 4
Paired box gene 4, also known as PAX4, is a protein which in humans is encoded by the PAX4 gene.
Gene data
PAX4- Name
- paired box 4
- Type
- protein-coding
- Position
- 127,610,292–127,618,142 (−)
- Aliases
- KPD, MODY9
- Ensembl
- ENSG00000106331
- RefSeq RNA
- NM_001366110.1, NM_001366111.1, NM_006193.2
- RefSeq protein
- NP_001353039.1, NP_001353040.1
This gene is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. These genes play critical roles during fetal development and cancer growth. The paired box 4 gene is involved in pancreatic islet development and mouse studies have demonstrated a role for this gene in differentiation of insulin-producing beta cells. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Cellular component
via MyGene.info
Gene · Ensembl
paired box 4
- Symbol
- PAX4
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 7:127,610,292-127,618,142
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 4515
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/5078
- genomic end
- 127618142
- genomic start
- 127250346
- expressed in
- ganglionic eminence
- chromosome
- human chromosome 7
- cytogenetic location
- 7q32.1
via Wikidata · CC0
~1 min read
Encyclopedic overview
5 sectionsContents
- Function
- See also
- References
- Further reading
- External links
Paired box gene 4, also known as PAX4, is a protein which in humans is encoded by the PAX4 gene.
== Function ==
Excerpted from Wikipedia’s “PAX4” article, available under the CC BY-SA 4.0 licence.