PCDH8
Sign in to saveAlso known as ARCADLIN, PAPC, protocadherin 8
Protocadherin-8 is a protein that in humans is encoded by the PCDH8 gene.
Gene data
PCDH8- Name
- protocadherin 8
- Type
- protein-coding
- Aliases
- ARCADLIN, PAPC
This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. The gene encodes an integral membrane protein that is thought to function in cell adhesion in a CNS-specific manner. Unlike classical cadherins, which are generally encoded by 15-17 exons, this gene includes only 3 exons. Notable is the large first exon encoding the extracellular region, including 6 cadherin domains and a transmembrane region. Alternative splicing yields isoforms with unique cytoplasmic tails. [provided by RefSeq, Jul 2008].
via MyGene.info
Gene · Ensembl
protocadherin 8
- Symbol
- PCDH8
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 13:52,842,889-52,848,641
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 1943
- exact match
- identifiers.org/ncbigene/5100
- genomic end
- 53422775
- genomic start
- 53418109
- cytogenetic location
- 13q14.3
Sources (3)
via Wikidata · CC0
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Article
2 sectionsContents
- References
- Further reading
Protocadherin-8 is a protein that in humans is encoded by the PCDH8 gene.
This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. The gene encodes an integral membrane protein that is thought to function in cell adhesion in a CNS-specific manner. Unlike classical cadherins, which are generally encoded by 15-17 exons, this gene includes only 3 exons. Notable is the large first exon encoding the extracellular region, including 6 cadherin domains and a transmembrane region. Alternative splicing yields isoforms with unique cytoplasmic tails.