pellagra
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Key facts
- Medical condition (new).name
- Pellagra
- Medical condition (new).image
- Pellagra2.jpg
- Medical condition (new).caption
- The skin features of pellagra including peeling, redness, scaling, and thickening of sun-exposed areas.
- Medical condition (new).field
- Dermatology
- Medical condition (new).symptoms
- Inflammation of the skin, diarrhea, dementia, sores in the mouth
- Medical condition (new).types
- Primary, secondary
- Medical condition (new).causes
- Not enough niacin
- Medical condition (new).diagnosis
- Based on symptoms
- Medical condition (new).differential
- Kwashiorkor, pemphigus, photodermatitis, porphyria
- Medical condition (new).prevention
- Consuming Niacin
- Medical condition (new).treatment
- Nicotinic acid or nicotinamide supplementation.
Article
12 sectionsContents
- Etymology
- Signs and symptoms
- Pathophysiology
- Treatment
- Epidemiology
- History
- United States
- Corn processing
- In popular culture
- References
- Further reading
- External links
Pellagra is a disease caused by a lack of the vitamin niacin (vitamin B3). Symptoms include inflamed skin, diarrhea, dementia, and sores in the mouth. Areas of the skin exposed to friction and radiation are typically affected first. Over time, affected skin may become darker, stiffen, peel, or bleed.
The two main types of pellagra are primary and secondary. Primary pellagra is due to a diet that does not contain enough niacin and tryptophan. Secondary pellagra is due to a poor ability to use the niacin within the diet. This can occur as a result of alcoholism, long-term diarrhea, carcinoid syndrome, Hartnup disease, and a number of medications such as isoniazid. Diagnosis is typically based on symptoms and may be assisted by urine testing.