Pfam
Sign in to savePfam is a database of protein families that includes their annotations and multiple sequence alignments generated using hidden Markov models. The latest version of Pfam, 37.0, was released in June 2024 and contains 21,979 families. It is currently provided through InterPro website.
Key facts
- Biodatabase.title
- Pfam
- Biodatabase.logo
- 120px
- Biodatabase.description
- The Pfam database provides alignments and hidden Markov models for protein domains.
- Biodatabase.scope
- Protein families
- Biodatabase.organism
- all
- Biodatabase.center
- EBI
- Biodatabase.pmid
- 19920124
- Biodatabase.format
- Stockholm format
- Biodatabase.download
- FTP
- Biodatabase.license
- GNU Lesser General Public License
- Biodatabase.bookmark
- yes
- Biodatabase.version
- 37.0
via Wikipedia infobox
~11 min read
Article
10 sectionsContents
- Uses
- Features
- Creation of new entries
- Domains of unknown function
- Clans
- History
- Community curation
- See also
- References
- External links
Pfam is a database of protein families that includes their annotations and multiple sequence alignments generated using hidden Markov models. The latest version of Pfam, 37.0, was released in June 2024 and contains 21,979 families. It is currently provided through InterPro website.
==Uses== The general purpose of the Pfam database is to provide a complete and accurate classification of protein families and domains. Originally, the rationale behind creating the database was to have a semi-automated method of curating information on known protein families to improve the efficiency of annotating genomes. The Pfam classification of protein families has been widely adopted by biologists because of its wide coverage of proteins and sensible naming conventions.