PHC1
Sign in to saveAlso known as EDR1, HPH1, MCPH11, RAE28, polyhomeotic homolog 1
Polyhomeotic-like protein 1 is a protein that in humans is encoded by the PHC1 gene.
Gene data
PHC1- Name
- polyhomeotic homolog 1
- Type
- protein-coding
- Position
- 8,913,824–8,944,860 (+)
- Aliases
- EDR1, HPH1, MCPH11, RAE28
- Ensembl
- ENSG00000111752
- RefSeq RNA
- NM_001413738.1, NM_001413739.1, NM_001413740.1, NM_001413741.1, NM_001413742.1
- RefSeq protein
- NP_001400667.1, NP_001400668.1, NP_001400669.1, NP_001400670.1, NP_001400671.1
This gene is a homolog of the Drosophila polyhomeotic gene, which is a member of the Polycomb group of genes. The gene product is a component of a multimeric protein complex that contains EDR2 and the vertebrate Polycomb protein BMH1. The gene product, the EDR2 protein, and the Drosophila polyhomeotic protein share 2 highly conserved domains, named homology domains I and II. These domains are involved in protein-protein interactions and may mediate heterodimerization of the protein encoded by this gene and the EDR2 protein. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Cellular component
Pathways
via MyGene.info
Gene · Ensembl
polyhomeotic homolog 1
- Symbol
- PHC1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 12:8,913,824-8,944,860
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 7 more facts
- HomoloGene ID
- 107079
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/1911
- genomic end
- 9094063
- genomic start
- 9066492
- chromosome
- human chromosome 12
- cytogenetic location
- 12p13.31
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
4 sectionsContents
- Function
- Interactions
- References
- Further reading
Polyhomeotic-like protein 1 is a protein that in humans is encoded by the PHC1 gene.
== Function ==
Excerpted from Wikipedia’s “PHC1” article, available under the CC BY-SA 4.0 licence.