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GeneQ17915827· pop 5· linked from 8 articles

Also known as EDR1, HPH1, MCPH11, RAE28, polyhomeotic homolog 1

Polyhomeotic-like protein 1 is a protein that in humans is encoded by the PHC1 gene.

Gene data

PHC1
Name
polyhomeotic homolog 1
Type
protein-coding
Position
8,913,824–8,944,860 (+)
Aliases
EDR1, HPH1, MCPH11, RAE28
RefSeq RNA
NM_001413738.1, NM_001413739.1, NM_001413740.1, NM_001413741.1, NM_001413742.1
RefSeq protein
NP_001400667.1, NP_001400668.1, NP_001400669.1, NP_001400670.1, NP_001400671.1

This gene is a homolog of the Drosophila polyhomeotic gene, which is a member of the Polycomb group of genes. The gene product is a component of a multimeric protein complex that contains EDR2 and the vertebrate Polycomb protein BMH1. The gene product, the EDR2 protein, and the Drosophila polyhomeotic protein share 2 highly conserved domains, named homology domains I and II. These domains are involved in protein-protein interactions and may mediate heterodimerization of the protein encoded by this gene and the EDR2 protein. [provided by RefSeq, Jul 2008].

via MyGene.info

Gene · Ensembl

polyhomeotic homolog 1

Symbol
PHC1
Biotype
Protein coding
Organism
Homo sapiens
Location
12:8,913,824-8,944,860
Strand
Forward (+)
Assembly
GRCh38
View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of
gene
Show 7 more facts
HomoloGene ID
107079
found in taxon
Homo sapiens
genomic end
9094063
genomic start
9066492
cytogenetic location
12p13.31
Sources (4)

via Wikidata · CC0

~1 min read

Encyclopedic overview

4 sections
Contents
  • Function
  • Interactions
  • References
  • Further reading

Polyhomeotic-like protein 1 is a protein that in humans is encoded by the PHC1 gene.

== Function ==

Excerpted from Wikipedia’s “PHC1” article, available under the CC BY-SA 4.0 licence.

Available in 5 languages

via Wikidata sitelinks · CC0