phloretin
Sign in to saveAlso known as 4-O-Methylphloracetophenone, 2,6-Dihydroxy-4-methoxyacetophenone, Dihydronaringenin, Phloretol, 3-(4-HYDROXYPHENYL)-1-(2,4,6-TRIHYDROXYPHENYL)PROPAN-1-ONE
Phloretin is a dihydrochalcone, a type of natural phenol. It can be found in apple tree leaves and the Manchurian apricot.
Research
2,499 papers- Phloretin, as a Potent Anticancer Compound: From Chemistry to Cellular Interactions.Molecules (Basel, Switzerland) · 2022
- Phloretin: a comprehensive review of its potential against diabetes and associated complications.The Journal of pharmacy and pharmacology · 2024
- Dermatological applications of the flavonoid phloretin.European journal of pharmacology · 2020
- Biochemical Basis of Anti-Cancer-Effects of Phloretin-A Natural Dihydrochalcone.Molecules (Basel, Switzerland) · 2019
- Phloretin-induced cytoprotective effects on mammalian cells: A mechanistic view and future directions.BioFactors (Oxford, England) · 2016
via PubMed
Wikidata facts
Show 4 more facts
- found in taxon
- broad bean
- chemical formula
- C₁₅H₁₄O₅
- canonical SMILES
- C1=CC(=CC=C1CCC(=O)C2=C(C=C(C=C2O)O)O)O
- has characteristic
- bitterness
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Encyclopedic overview
6 sectionsContents
- Metabolism
- Pharmacological research
- Nanoparticle synthesis
- Glycosides
- See also
- References
Phloretin is a dihydrochalcone, a type of natural phenol. It can be found in apple tree leaves and the Manchurian apricot.
== Metabolism == In rats, ingested phlorizin is converted into phloretin by hydrolytic enzymes in the small intestine. Phloretin hydrolase hydrolyses phloretin into phloretic acid and phloroglucinol.
Excerpted from Wikipedia’s “phloretin” article, available under the CC BY-SA 4.0 licence.