Structure via PubChem · Public domain (PubChem)
فلورتین
Sign in to saveAlso known as 4-O-Methylphloracetophenone, 2,6-Dihydroxy-4-methoxyacetophenone, Dihydronaringenin, Phloretol, 3-(4-HYDROXYPHENYL)-1-(2,4,6-TRIHYDROXYPHENYL)PROPAN-1-ONE
Phloretin is a dihydrochalcone, a type of natural phenol. It can be found in apple tree leaves and the Manchurian apricot.
Chemical data
- Formula
- C15H14O5
- Molecular weight
- 274.27 g/mol
- IUPAC name
- 3-(4-hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)propan-1-one
- SMILES
- C1=CC(=CC=C1CCC(=O)C2=C(C=C(C=C2O)O)O)O
- InChIKey
- VGEREEWJJVICBM-UHFFFAOYSA-N
- XLogP
- 2.6
- Polar surface area
- 98 Ų
- H-bond donors
- 4
- H-bond acceptors
- 5
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Molecule type
- Small molecule
via ChEMBL · EBI
Research
2,499 papers- Phloretin, as a Potent Anticancer Compound: From Chemistry to Cellular Interactions.Molecules (Basel, Switzerland) · 2022
- Phloretin: a comprehensive review of its potential against diabetes and associated complications.The Journal of pharmacy and pharmacology · 2024
- Dermatological applications of the flavonoid phloretin.European journal of pharmacology · 2020
- Biochemical Basis of Anti-Cancer-Effects of Phloretin-A Natural Dihydrochalcone.Molecules (Basel, Switzerland) · 2019
- Phloretin-induced cytoprotective effects on mammalian cells: A mechanistic view and future directions.BioFactors (Oxford, England) · 2016
via PubMed
Wikidata facts
Show 4 more facts
- found in taxon
- broad bean
- chemical formula
- C₁₅H₁₄O₅
- canonical SMILES
- C1=CC(=CC=C1CCC(=O)C2=C(C=C(C=C2O)O)O)O
- has characteristic
- bitterness
via Wikidata · CC0