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phosphoramidite

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Also known as phosphoramidites

thumbnail|right|Phosphoramidite: general structure A phosphoramidite (RO)2PNR2 is a monoamide of a phosphite diester. The key feature of phosphoramidites is their markedly high reactivity towards nucleophiles catalyzed by weak acids e.c., triethylammonium chloride or 1H-tetrazole. In these reactions, the incoming nucleophile replaces the NR2 moiety.

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Phosphoramidites
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5 sections
Contents
  • Applications
  • Nucleoside phosphoramidites
  • As ligands
  • See also
  • References

thumbnail|right|Phosphoramidite: general structure A phosphoramidite (RO)2PNR2 is a monoamide of a phosphite diester. The key feature of phosphoramidites is their markedly high reactivity towards nucleophiles catalyzed by weak acids e.c., triethylammonium chloride or 1H-tetrazole. In these reactions, the incoming nucleophile replaces the NR2 moiety.

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