piericidin A

Chemical data

Formula

C25H37NO4

Molecular weight

415.6 g/mol

IUPAC name

2-[(2E,5E,7E,9R,10R,11E)-10-hydroxy-3,7,9,11-tetramethyltrideca-2,5,7,11-tetraenyl]-5,6-dimethoxy-3-methyl-1H-pyridin-4-one

SMILES

C/C=C(\C)/[C@@H]([C@H](C)/C=C(\C)/C=C/C/C(=C/CC1=C(C(=O)C(=C(N1)OC)OC)C)/C)O

InChIKey

BBLGCDSLCDDALX-LKGBESRRSA-N

XLogP

6.1

Polar surface area

67.8 Ų

H-bond donors

2

H-bond acceptors

5

Formal charge

0

via PubChem

Drug data · ChEMBL

Molecule type

Small molecule

via ChEMBL · EBI

• Piericidin A aggravates Tau pathology in P301S transgenic mice.PloS one · 2014
• Iakyricidins A-D, Antiproliferative Piericidin Analogues Bearing a Carbonyl Group or Cyclic Skeleton from Streptomyces iakyrus SCSIO NS104.The Journal of organic chemistry · 2019
• New piericidin glucosides, glucopiericidins A and B.The Journal of antibiotics · 1987
• Piericidin A: a new inhibitor of mitochondrial electron transport.Biochemical and biophysical research communications · 1966
• Efficacies of quorum sensing inhibitors, piericidin A and glucopiericidin A, produced by Streptomyces xanthocidicus KPP01532 for the control of potato soft rot caused by Erwinia carotovora subsp. atroseptica.Microbiological research · 2016

via PubMed

Wikidata facts

Mass

415.272

via Wikidata · CC0